How to manage erythema with a small open area at home?

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Last updated: October 31, 2025View editorial policy

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Home Management of Erythema with Small Open Area

For erythema with a small open area at home, use a dispersible cream as a soap substitute, apply emollients after bathing, and use the least potent topical corticosteroid that effectively controls symptoms. 1

Initial Assessment and Cleansing

  • Avoid regular soaps and detergents as they remove natural lipids from the skin surface, which is particularly problematic for already dry skin 1
  • Use a dispersible cream as a soap substitute to cleanse the affected area 1
  • Gently clean the area before applying any treatment 2
  • Look for signs of infection such as crusting, weeping, or grouped punched-out erosions which may indicate bacterial or viral infection 1

First-Line Treatment

  • Apply emollients after bathing to provide a surface lipid film that retards evaporative water loss from the epidermis 1
  • Use the least potent topical corticosteroid preparation required to control symptoms 1
  • Apply topical treatments no more than twice daily (some newer preparations require only once daily application) 1
  • For adults and children over 2 years: apply a small amount of topical treatment (equal to the surface area of a fingertip) to the affected area 1-3 times daily 2
  • The area may be covered with a sterile bandage if needed 2

Management of Secondary Infection

  • If bacterial infection is suspected (indicated by crusting or weeping):

    • Flucloxacillin is usually the most appropriate antibiotic for treating Staphylococcus aureus 1
    • Use erythromycin when there is resistance to flucloxacillin or in patients with penicillin allergy 1
    • Phenoxymethylpenicillin should be given if β-hemolytic streptococci are isolated 1
  • If viral infection (herpes simplex) is suspected (indicated by grouped, punched-out erosions):

    • Oral acyclovir should be given early in the course of the disease 1, 3
    • For ill, febrile patients with eczema herpeticum, intravenous acyclovir is required 1, 3

Additional Supportive Measures

  • Keep nails short to prevent scratching and secondary infection 1
  • Avoid extremes of temperature which can exacerbate symptoms 1
  • Avoid irritant clothing such as wool; cotton clothing is more comfortable and recommended 1
  • For severe itching, sedating antihistamines may be useful as a short-term adjuvant during flares 1

When to Seek Medical Attention

  • If there is no improvement with home treatment after a few days 1
  • If there are signs of spreading infection (increasing redness, warmth, pain) 1
  • If fever develops, especially with grouped vesicles or erosions (may indicate eczema herpeticum requiring urgent treatment) 3
  • If there is diagnostic uncertainty about the cause of the erythema 1

Special Considerations for Different Types of Erythema

  • For lichenified eczema, ichthammol (1% in zinc ointment) or coal tar preparations may be particularly useful 1
  • For dyshidrotic eczema (on hands/feet), medium to high potency topical corticosteroids may be needed for acute flares, followed by tapering to maintenance therapy 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Eczema Herpeticum with Fever

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Dyshidrotic Eczema

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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