What is the cause of recurrent sinusitis and diarrhea in an 80-year-old male?

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Last updated: March 27, 2025 • View editorial policy

Differential Diagnosis for 80-year-old Male with Recurring Sinusitis and Gastrointestinal Symptoms

  • Single Most Likely Diagnosis + Chronic sinusitis: The patient's symptoms of continuous nasal congestion, drainage, and postnasal drainage, which worsened after stopping the Medrol Dosepak, suggest a chronic condition that was temporarily improved with corticosteroids but not fully resolved. The recurrence of symptoms after stopping treatment is common in chronic conditions.
  • Other Likely Diagnoses + Bacterial sinusitis: Given the patient's recent history of sinusitis and the worsening of symptoms, a bacterial infection could be a cause, especially if the initial treatment with the Medrol Dosepak (which is anti-inflammatory) did not address an underlying bacterial cause. + Viral gastroenteritis: The patient's symptoms of diarrhea, soft stool, and abdominal soreness without fever could be indicative of a viral gastrointestinal infection, which is common and can occur concurrently with or independently of the sinusitis. + Irritable Bowel Syndrome (IBS): The gastrointestinal symptoms could also suggest IBS, especially if the patient has a history of similar symptoms or if the diarrhea and abdominal soreness persist without an identifiable infectious cause.
  • Do Not Miss Diagnoses + Invasive fungal sinusitis: Although less likely, this condition can be deadly, especially in immunocompromised patients. The patient's age and recent corticosteroid use could potentially increase his risk for fungal infections. + Clostridioides difficile (C. diff) infection: Given the patient's recent use of corticosteroids and potential exposure to antibiotics (though not mentioned, it's a common treatment for sinusitis), C. diff infection is a critical diagnosis not to miss, as it can cause severe diarrhea and has a high morbidity and mortality rate in elderly patients. + Gastrointestinal bleeding or obstruction: Although the patient denies abdominal pain or fever, any gastrointestinal symptom in an elderly patient warrants consideration of more serious conditions like bleeding or obstruction, which could present atypically.
  • Rare Diagnoses + Allergic fungal sinusitis: This is a rare condition that could explain the patient's sinus symptoms, especially if he has a history of allergies. However, it is less common and would typically require specific diagnostic testing. + Eosinophilic esophagitis or gastroenteritis: These conditions are rare and could potentially explain some of the patient's gastrointestinal symptoms, especially if there's an allergic component. However, they are less likely and would require specific diagnostic evaluation.

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