What is the effect of Ecdysterone (a phytoecdysteroid)?

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Last updated: March 27, 2025View editorial policy

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From the Research

Ecdysterone has been shown to have a significant anabolic effect in humans, increasing muscle mass and strength, and may also have potential benefits in the treatment of breast cancer, as evidenced by the most recent and highest quality study 1. The effects of ecdysterone on human health have been studied in various contexts, including its potential as a performance-enhancing supplement and its possible medical benefits. Some studies have suggested that ecdysterone may have anabolic effects in humans, similar to those of anabolic steroids, but without the same side effects 2, 3.

  • The anabolic effects of ecdysterone are thought to be mediated by its binding to estrogen receptors, which activates anabolic pathways and stimulates muscle growth 2, 3.
  • Ecdysterone has also been shown to have potential benefits in the treatment of breast cancer, with one study finding that it inhibited the growth of breast cancer cells and induced autophagy 4.
  • However, the scientific evidence for the effects of ecdysterone is still limited and preliminary, and more research is needed to fully understand its potential benefits and risks 5, 1.
  • Users of ecdysterone supplements should be aware that they are not strictly regulated by the FDA, and quality can vary between products, and long-term safety data is lacking 2, 1.
  • Those considering ecdysterone should consult with a healthcare provider before use, especially individuals with hormone-sensitive conditions, pregnant or nursing women, and those taking medications that might interact with it 2, 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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