What form of magnesium is recommended for mood stabilization, sleep regulation, and muscle recovery?

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Last updated: March 27, 2025View editorial policy

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From the Research

Magnesium L-threonate is the most recommended form of magnesium for mood stabilization, sleep regulation, and muscle recovery, as evidenced by the most recent and highest quality study 1.

Key Benefits of Magnesium L-threonate

  • Improves sleep quality, especially deep and REM sleep stages
  • Improves mood, energy, alertness, and daily activity and productivity
  • High bioavailability and brain penetration, making it effective for neuronal health
  • Safe and well-tolerated, with minimal side effects

Comparison with Other Forms of Magnesium

  • Magnesium glycinate is also a popular form of magnesium, but it may not have the same level of brain penetration and bioavailability as Magnesium L-threonate 2, 3, 4
  • Magnesium citrate and other forms of magnesium may have a laxative effect and may not be as well-tolerated as Magnesium L-threonate

Recommended Dosage and Administration

  • A typical dose of Magnesium L-threonate ranges from 1-2 grams daily, taken in the evening for sleep benefits or divided throughout the day
  • Take with food to enhance absorption and minimize side effects
  • Start with a lower dose to assess tolerance and adjust as needed

Clinical Evidence and Recommendations

  • The most recent and highest quality study 1 supports the use of Magnesium L-threonate for mood stabilization, sleep regulation, and muscle recovery
  • Other studies 2, 3, 4, 5 provide additional evidence for the benefits of magnesium supplementation, but may not be as specific to Magnesium L-threonate
  • Based on the available evidence, Magnesium L-threonate is the recommended form of magnesium for mood stabilization, sleep regulation, and muscle recovery.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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