What is the recommended dose of ibuprofen (nonsteroidal anti-inflammatory drug (NSAID)) for a 10-year-old child weighing 145 pounds?

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Ibuprofen Dosing for a 10-Year-Old Weighing 145 Pounds

The recommended dose of ibuprofen for a 10-year-old child weighing 145 pounds (66 kg) is 600 mg every 8 hours, not to exceed 2400 mg per day. 1

Dosing Considerations Based on Weight and Age

  • For children weighing more than 40 kg (88 lb), adult dosing should be used 1
  • The standard pediatric dose of ibuprofen is 10 mg/kg every 8 hours 2, 1
  • For this 10-year-old weighing 145 pounds (66 kg):
    • Calculated dose: 10 mg/kg × 66 kg = 660 mg
    • Rounded to standard adult dose: 600 mg per dose 1
    • Maximum frequency: Every 8 hours (3 times daily) 2, 1
    • Maximum daily dose: 2400 mg/day 1

Administration Guidelines

  • Ibuprofen should be given with food or milk to minimize gastrointestinal side effects 3
  • The oral route is preferred over rectal administration due to more reliable absorption 4
  • Each dose should be carefully measured and recorded to avoid accidentally exceeding the maximum recommended dose 5

Safety Considerations

  • Ibuprofen has been shown to be as effective as or more effective than acetaminophen for pain and fever relief with a longer duration of action 6
  • Monitor for potential side effects including:
    • Gastrointestinal discomfort or pain
    • Nausea
    • Potential renal effects with prolonged use 3
  • Ensure adequate hydration while taking ibuprofen 4
  • Short-term use at recommended doses has a good safety profile 3

Common Pitfalls to Avoid

  • Parental misdosing is common (51% in one study), particularly underdosing which can lead to inadequate symptom relief 7
  • Weight-based dosing is more accurate than age-based dosing, especially for children who are larger or smaller than average for their age 7
  • Avoid exceeding the maximum daily dose of 40 mg/kg/day or 2400 mg/day (whichever is less) 1
  • Do not administer ibuprofen concurrently with other NSAIDs as this increases risk of side effects 3

References

Guideline

Dosis de Ibuprofeno Pediátrico

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ibuprofen: pharmacology, efficacy and safety.

Inflammopharmacology, 2009

Research

A general overview of the use of ibuprofen in paediatrics.

International journal of clinical practice. Supplement, 2003

Research

Acetaminophen and ibuprofen dosing by parents.

Pediatric emergency care, 2000

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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