Initial Treatment for Avulsed Skin
The initial treatment for avulsed skin should include gentle cleansing of the wound with warmed sterile water or saline, decompressing any blisters while leaving the detached epidermis in place as a biological dressing, and applying nonadherent dressings to the denuded dermis. 1
Assessment and Preparation
- Gently cleanse the avulsed skin and wound bed by irrigating with warmed sterile water, saline, or dilute antimicrobial solution such as chlorhexidine (1/5000) to remove debris while minimizing trauma 1
- Take swabs for bacterial and candidal culture from sloughy or crusted areas to guide antimicrobial therapy if infection is suspected 1, 2
- Decompress any blisters by piercing and expressing or aspirating fluid, but leave the detached epidermis in place to act as a biological dressing 1
Primary Management Approach
Conservative Management
- Leave the detached, lesional epidermis in situ to act as a biological dressing whenever possible 1
- Apply a greasy emollient, such as 50% white soft paraffin with 50% liquid paraffin, over the whole epidermis, including denuded areas 1
- Consider using aerosolized formulations of emollients to minimize shearing forces associated with topical applications 1
- Avoid preparations containing sensitizers or irritants that may further damage compromised skin 1, 2
Dressing Application
- Apply nonadherent dressings directly to denuded dermis (suitable options include Mepitel™ or Telfa™) 1, 2
- Use a secondary foam or specialized burn dressing to collect exudate (suitable options include Exu-Dry™) 1, 2
- Apply topical antimicrobial agents only to sloughy areas, not as routine prophylaxis 1
- Consider silver-containing products or dressings for wounds showing signs of critical colonization or local infection, but limit use due to potential systemic absorption 1, 2
Advanced Management Options
For Extensive Avulsion Injuries
- For large avulsed skin flaps, particularly in degloving injuries, consider defatting the avulsed skin and reattaching it to the original position 3
- Negative pressure wound therapy can be applied over reattached skin as a bolster to improve graft take 3, 4
- For complex wound geometries, gauze-based wound fillers can be easily applied for skin graft immobilization with negative pressure therapy 4
For Non-Viable Avulsed Skin
- If the avulsed skin is non-viable, consider removing it and using it as a full-thickness or split-thickness skin graft 5
- In some cases, thin split-thickness skin grafting can be performed twice from the same piece of avulsed skin to maximize coverage 6
- Artificial dermis may be considered as a dermal regeneration template for skin avulsion injuries with compromised perfusion 7
Monitoring and Follow-up
- Monitor the wound regularly for signs of infection such as increased pain, confusion, hypotension, reduced urine output, or reduced oxygen saturation 1
- Administer systemic antibiotics only if there are clinical signs of infection, not prophylactically 1, 2
- Be alert to a monoculture of organisms detected on previously mixed growth cultures, which may indicate one strain becoming predominant and increased risk of invasive infection 1, 2
- Consider re-exploration of the wound within 12-24 hours if there are signs of infection or necrosis 1
Important Caveats
- Handle avulsed skin with extreme care to minimize shearing forces that could further damage tissue 1
- Avoid overaggressive debridement of viable tissue during initial management 1
- For avulsions involving specialized tissue (such as plantar surface), consider revascularization rather than simple reattachment or grafting 5
- Regular reassessment is critical - monitor the wound for signs of improvement and change treatment approach if healing is delayed 2