Differential Diagnosis for Lumps in Skin, Indurated and Intermittently Painful
Single Most Likely Diagnosis
- Furuncle or Carbuncle: These are skin infections of a hair follicle or a group of hair follicles, respectively, that can cause indurated and painful lumps. They are common and can occur anywhere on the body, especially in areas prone to sweating or friction.
Other Likely Diagnoses
- Cyst: Sebaceous or epidermoid cysts can become inflamed and cause painful, indurated lumps. They are benign but can become infected, leading to increased pain and swelling.
- Abscess: A collection of pus that has built up within the tissue of the body, which can cause a painful, indurated lump. Abscesses can occur anywhere and are usually a result of a bacterial infection.
- Lipoma: Although typically benign and painless, lipomas can occasionally cause pain if they press on nearby nerves or if they become inflamed. They are common and can appear as indurated lumps under the skin.
Do Not Miss Diagnoses
- Cellulitis: An infection of the skin and subcutaneous tissues that can cause redness, swelling, and pain. It can progress rapidly and lead to serious complications if not treated promptly.
- Necrotizing Fasciitis: A severe infection that destroys the tissue under the skin, including fat and the tissue covering the muscles (fascia). It is a medical emergency and requires immediate attention.
- Malignancy (e.g., Squamous Cell Carcinoma, Basal Cell Carcinoma): Although less common, skin cancers can present as indurated and occasionally painful lumps. Early detection is crucial for effective treatment.
Rare Diagnoses
- Panniculitis: Inflammation of the subcutaneous fat, which can cause painful, indurated lumps. It can be caused by various factors, including autoimmune diseases, infections, and trauma.
- Erythema Nodosum: A condition characterized by the sudden formation of painful, indurated lumps under the skin, typically on the shins. It can be associated with various underlying conditions, including infections, autoimmune diseases, and medications.
- Dermatofibroma: A benign skin growth that can appear as a firm, indurated lump, often following minor injury, and can be painful if pressed or if it grows rapidly.