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Differential Diagnosis for Swollen Lower Neck

Single Most Likely Diagnosis

  • Reactive lymphadenopathy: This is the most common cause of swollen neck, often due to a viral or bacterial infection, which leads to the enlargement of lymph nodes as the body responds to the infection.

Other Likely Diagnoses

  • Tonsillitis: Inflammation of the tonsils can cause swelling in the neck due to the enlargement of lymph nodes in response to the infection.
  • Mononucleosis (Mono): Caused by the Epstein-Barr virus, mono can lead to swollen lymph nodes in the neck, among other symptoms like fever and sore throat.
  • Dental infections: Abscesses or infections in the teeth or gums can cause swelling in the neck due to the spread of infection to the lymph nodes.
  • Thyroiditis: Inflammation of the thyroid gland can cause swelling in the lower part of the neck.

Do Not Miss Diagnoses

  • Lymphoma: Although less common, lymphoma (cancer of the lymphatic system) can cause swollen lymph nodes in the neck and is critical to diagnose early.
  • Metastatic cancer: Cancer that has spread to the lymph nodes in the neck from another part of the body can cause swelling and is crucial to identify for appropriate treatment.
  • Tuberculosis (TB): TB can cause swollen lymph nodes, especially in the neck, and is important to diagnose due to its infectious nature and the need for specific treatment.
  • Abscess or infected cyst: A collection of pus in the neck can cause severe swelling and requires prompt drainage to prevent complications.

Rare Diagnoses

  • Sarcoidosis: A condition that can cause inflammation in various parts of the body, including the lymph nodes in the neck, leading to swelling.
  • Kawasaki disease: A rare condition that mainly affects children, causing inflammation in the walls of medium-sized arteries throughout the body, and can lead to swollen lymph nodes in the neck.
  • Castleman disease: A rare disorder that involves an overgrowth of cells in the body's lymph nodes, which can cause swelling in the neck.
  • Cystic hygroma: A rare congenital condition that can cause swelling in the neck due to a fluid-filled sac.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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