From the FDA Drug Label
Warnings For external use only ... If swallowed, get medical help or contact a Poison Control Center right away. The risk of toxicity from ingesting one over-the-counter (OTC) boric acid supplement orally is unknown but potentially severe.
- Key points:
- The label warns against ingestion
- It advises to get medical help or contact a Poison Control Center right away if swallowed Given the warning for external use only and the advice to seek medical help if ingested, it is clear that ingestion poses a risk, but the exact level of toxicity is not specified in the label 1.
From the Research
Taking a single over-the-counter boric acid supplement orally poses significant toxicity risks and should be avoided. Boric acid supplements are intended for vaginal use only and should never be taken by mouth. Oral ingestion of boric acid can cause acute poisoning with symptoms including nausea, vomiting, diarrhea, skin rash, and in severe cases, kidney damage, seizures, and even death. The toxic oral dose can be as low as 5-6 grams for adults, and some supplements contain 600mg per capsule.
Key Points to Consider
- If you've accidentally ingested boric acid, contact Poison Control immediately at 1-800-222-1222.
- For vaginal health concerns that might lead someone to consider boric acid, consult a healthcare provider for appropriate treatment options.
- Boric acid is only considered safe when used as directed for vaginal infections in specific formulations designed for that purpose, not as an oral supplement.
- The toxicity occurs because when taken orally, boric acid is absorbed into the bloodstream at much higher levels than when used vaginally, leading to systemic effects throughout the body, as seen in cases reported in the literature 2, 3, 4, 5, 6.
Treatment and Prevention
- Early treatment with forced diuresis and haemodialysis may be considered for boric acid poisoning, even if signs of renal dysfunction are not apparent, to prevent severe renal damage and its complications 3.
- Forced diuresis without haemodialysis is recommended early after admission for boric acid poisoning 4.
- It is essential to note that the risk of toxicity from ingesting one over-the-counter boric acid supplement orally can be significant, and immediate medical attention is necessary in case of accidental ingestion.
Evidence-Based Recommendation
Based on the most recent and highest quality study available, the risk of toxicity from ingesting one over-the-counter boric acid supplement orally is significant, and it should be avoided 3.