Management of Stroke Patients
The most effective approach to stroke management involves rapid recognition, immediate activation of emergency medical services, and treatment in a specialized stroke unit with a multidisciplinary team to reduce mortality and improve outcomes. 1
Initial Assessment and Stabilization
- Triage stroke patients with the same priority as patients with acute myocardial infarction or serious trauma, regardless of deficit severity 2
- Immediately stabilize airway, breathing, and circulation (ABCs) followed by assessment of neurological deficits 2
- Determine time of symptom onset - defined as when the patient was last at baseline or symptom-free state 2
- Implement stroke pathways and notify stroke team early in parallel with ED evaluation 2
- Perform neuroimaging urgently (CT or MRI) within 24 hours to rule out hemorrhage and determine eligibility for reperfusion therapies 1
Acute Treatment
- For eligible patients with ischemic stroke, administer intravenous alteplase within 4.5 hours of symptom onset 1
- Consider mechanical thrombectomy for patients with large vessel occlusion within 6-24 hours based on specific imaging criteria 1
- Blood pressure management:
Stroke Unit Care
- Admit all stroke patients to a geographically defined stroke unit with specialized staff 1
- Provide care through an interdisciplinary team with expertise in stroke management 1
- Monitor neurological status and vital signs frequently during the first 24 hours 1
- Implement standardized stroke orders or integrated stroke pathways to improve adherence to best practices 1
Management of Complications
Dysphagia and Aspiration Prevention
- Perform swallowing screening within 24 hours of admission using a validated tool before giving food, fluids, or oral medications 1, 2
- Implement appropriate dietary modifications based on swallowing assessment results 2
- Consider techniques such as chin tuck, small sips, multiple swallows, and upright positioning for patients with dysphagia 2
Neurological Complications
- Monitor closely for signs of neurological deterioration 2
- For cerebral edema and increased intracranial pressure:
- Monitor for and treat seizures with antiseizure medications when documented (prophylactic seizure medication is not recommended) 2
Other Complications
- Actively monitor and manage fever and hyperglycemia 1
- Implement early mobilization to prevent complications such as pneumonia, deep vein thrombosis, and pressure sores 1
- Implement frequent turning, use alternating pressure mattresses, and closely monitor skin to prevent pressure sores 1
- Ensure proper hydration and nutrition to prevent dehydration, which can slow recovery and increase risk of deep vein thrombosis 1
Rehabilitation
- Begin rehabilitation assessment by specialized professionals within 48 hours of admission 1
- Start rehabilitation therapy as soon as the patient is medically stable 1
- Implement a comprehensive approach including physical, occupational, and speech therapy 3
- Consider community-based rehabilitation options which can be as effective as hospital-based programs 1
Secondary Prevention
- Start aspirin 160-300 mg/day within 48 hours of onset for ischemic stroke patients not receiving thrombolysis 1
- Consider carotid endarterectomy for patients with recent carotid artery territory ischemic stroke with ipsilateral stenosis of 70-99% (ideally within 2 weeks) 1
- Identify and manage modifiable risk factors including hypertension, diabetes, hyperlipidemia, and smoking 1
Public Education and Prevention
- Promote awareness of stroke warning symptoms and the importance of calling emergency services immediately 4, 5
- Use the FAST mnemonic (Face, Arm, Speech, Time to call emergency services) to increase public recognition of stroke symptoms 1
- Emphasize that "time is brain" - any delay in starting therapy after acute stroke results in progressive, irreversible loss of brain tissue 5
Healthcare System Organization
- Develop efficient processes and pathways to manage stroke patients in ED and inpatient settings 2
- Implement local protocols for early notification by paramedics, high-priority transportation, and rapid access to imaging 1
- Participate in quality improvement programs like Get With The Guidelines-Stroke to improve care processes and adherence to stroke performance measures 1