Management of Difficult Vascular Access (Difficult Cannulation/Branula)
When peripheral IV access is difficult, the primary alternatives are ultrasound-guided peripheral IV placement, intraosseous (IO) access for emergencies, or central venous catheterization depending on clinical urgency and anticipated duration of access.
Immediate Alternative Access Options
Ultrasound-Guided Peripheral IV Access
- This should be the first-line alternative for difficult peripheral access in non-emergency situations, as it significantly improves success rates while maintaining the safety profile of peripheral access 1
- Targets deeper veins (basilic, brachial) that are not visible or palpable on standard examination 1
- Particularly useful in patients with obesity, IV drug use history, chronic illness, or edema 1
Intraosseous (IO) Access
- IO access is the preferred emergency alternative when immediate vascular access is needed and peripheral attempts have failed, particularly in critically ill or arrested patients 1
- Can be placed in the proximal tibia, distal tibia, or proximal humerus within seconds 1
- Allows administration of all medications, fluids, and blood products that can be given IV 1
- Should be considered temporary (typically <24 hours) and transitioned to definitive access once patient is stabilized 1
Central Venous Catheterization
- Reserved for patients requiring:
- Common sites include internal jugular, subclavian, or femoral veins 1
- Carries higher complication risks (pneumothorax, arterial puncture, infection) compared to peripheral access 1
Clinical Decision Algorithm
Step 1: Assess Clinical Urgency
- Emergency/resuscitation situation: Proceed directly to IO access 1
- Urgent but stable: Attempt ultrasound-guided peripheral IV 1
- Non-urgent: Consider ultrasound-guided peripheral IV or central line based on anticipated duration and medication requirements 1
Step 2: Consider Patient-Specific Factors
- Anticipated duration of therapy:
- Type of medications needed:
Step 3: Reassess After Initial Intervention
- If IO placed emergently, transition to peripheral or central access within 24 hours once patient stabilized 1
- If ultrasound-guided peripheral fails, escalate to central venous access 1
Common Pitfalls to Avoid
- Repeated blind peripheral attempts: After 2-3 failed attempts, escalate to ultrasound guidance or alternative access rather than continuing blind attempts, which increases patient discomfort and vein damage 1
- Delaying IO access in emergencies: Do not waste time with multiple peripheral attempts in critically ill patients when IO can be placed in seconds 1
- Inappropriate IO duration: IO access should not remain in place beyond 24 hours due to increased complication risk 1
- Underutilizing ultrasound guidance: Many facilities have ultrasound readily available but providers default to blind attempts when ultrasound-guided access has superior success rates 1
Special Considerations
- In patients with chronic difficult access (dialysis patients, oncology patients, chronic illness), early consultation for PICC or port placement may prevent repeated access difficulties 1
- Pediatric patients may benefit from IO access more readily than adults in emergency situations due to easier landmark identification 1