How Long Can You Use an Ozempic Pen?
Storage Duration After First Use
An Ozempic pen can be used for 56 days (8 weeks) after first use, regardless of whether medication remains in the pen, and must be discarded after this period even if not empty. 1
Storage Conditions During Use
Once you start using an Ozempic pen, you have two storage options for the 56-day period:
- Room temperature storage: Between 59°F to 86°F (15°C to 30°C) 1
- Refrigerator storage: Between 36°F to 46°F (2°C to 8°C) 1
Both storage methods are acceptable during the 56-day use period, giving you flexibility based on convenience and travel needs. 1
Before First Use (Unopened Pens)
- Unopened pens must be refrigerated between 36°F to 46°F (2°C to 8°C) 1
- Can be used until the expiration date printed on the label if kept refrigerated 1
- When refrigerating, do not store directly next to the cooling element 1
Critical Storage Rules
Never freeze Ozempic - if it has been frozen, discard it immediately as freezing destroys the medication's potency. 1
Protect from extreme temperatures - avoid exposing the pen to temperatures below 36°F or above 86°F, as this leads to loss of potency. 2
Keep away from light - always replace the pen cap after each use to protect the medication from light exposure. 1
Practical Tracking Recommendation
Write the disposal date on your calendar when you first use a new pen - count 56 days from first use and mark this as the mandatory discard date. 1 This prevents accidentally using expired medication, which may result in unexplained blood glucose increases due to reduced potency. 2
Needle Management
Always remove and dispose of the needle after each injection - leaving needles attached between doses increases risk of contamination, infection, medication leakage, and blocked needles that prevent proper dosing. 1
Use a new needle for every injection to ensure proper medication delivery and reduce infection risk. 1
Signs of Compromised Medication
Before each injection, inspect the medication through the pen window:
- Should be clear and colorless 1
- Do not use if cloudy or contains particles 1
- Unexplained blood glucose increases may indicate reduced medication potency from improper storage 2
If you suspect any problem with your pen (such as dropping it on a hard surface), attach a new needle and check medication flow before injecting. 1
Travel Considerations
Always keep your pen with you - do not leave it in a car or other location where it can get too hot or too cold, as temperature extremes destroy the medication. 1
Carry an extra pen and new needles when traveling in case of loss or damage. 1