How Long Does a Wegovy Pen Last?
Each Wegovy (semaglutide 2.4 mg) pen is designed for a single weekly injection and contains one dose, meaning you will need a new pen for each weekly administration. 1
Dosing Schedule and Pen Usage
Wegovy follows a specific titration schedule over 16-20 weeks before reaching the maintenance dose 1:
- Weeks 1-4: 0.25 mg once weekly (one pen per week)
- Weeks 5-8: 0.5 mg once weekly (one pen per week)
- Weeks 9-12: 1.0 mg once weekly (one pen per week)
- Weeks 13-16: 1.7 mg once weekly (one pen per week)
- Week 17 onward: 2.4 mg once weekly (one pen per week) - maintenance dose 1
Practical Considerations
Each pen contains exactly one dose and should be discarded after a single use, regardless of the dose strength. 1 This means:
- You will use one pen per week throughout your entire treatment
- A monthly supply consists of approximately 4 pens (one for each week)
- The pen is not refillable or reusable 1
Storage and Handling
- Store unused pens in the refrigerator until needed 2
- Once removed from refrigeration for use, the pen should be used for that week's injection
- The medication is administered subcutaneously once weekly 2, 1
Missed Dose Guidance
If you miss 2 consecutive doses, clinical judgment is required for subsequent dosing, and resuming at the same dose can be considered if you tolerated the medication well previously. 1 If 3 or more consecutive doses are missed, consider restarting the titration schedule from the beginning. 1
Cost Implications
The average wholesale price is approximately $1,619 for a 30-day supply (4 weekly pens), with a National Average Drug Acquisition Cost of approximately $1,294-$1,295 per month. 2 This translates to roughly $400-$450 per individual pen at wholesale pricing.