What is the brand name of the umeclidinium (Long-Acting Muscarinic Antagonist (LAMA))/vilanterol (Long-Acting Beta-Agonist (LABA)) inhaler?

Brand Name of Umeclidinium/Vilanterol Inhaler

The brand name of the umeclidinium/vilanterol inhaler is Anoro Ellipta (marketed as Anoro Ellipta in the USA and Canada, and as Laventair in some European markets). 1, 2, 3

Product Details

• Active ingredients: Umeclidinium bromide 62.5 mcg and vilanterol trifenatate 25 mcg (equivalent to delivered doses of 55 mcg umeclidinium and 22 mcg vilanterol) 1

• Device: Ellipta multi-dose dry powder inhaler, which is a light grey and red plastic inhaler containing 2 foil blister strips 1

• Dosing frequency: Once-daily administration 2, 3

Regulatory Approval

• First global approval: Received initial approval in the USA for maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema 3

• Subsequent approvals: Canada, with regulatory submissions under review in Europe and Japan as of 2014 3

• Current availability: Available in Japan, USA, Canada, and EU countries 2

Clinical Context

• Drug classes: Combines a long-acting muscarinic antagonist (LAMA) with a long-acting β2-adrenoceptor agonist (LABA) 2, 4

• Indication: Oral inhalation for maintenance therapy in adults with COPD 2, 3

• Guidelines recognition: The American College of Chest Physicians and Canadian Thoracic Society guidelines note that umeclidinium/vilanterol was approved by the FDA for COPD as once-daily combination bronchodilator therapy 5