What is the diagnosis for a patient with a computed tomography (CT) abdomen scan showing an enlarged, fatty liver and non-aneurysmal atherosclerosis, urinalysis indicating glycosuria (glucose in urine), hematuria (blood in urine), and pyuria (white blood cells in urine), with a comprehensive metabolic panel (CMP) showing hyperglycemia (elevated glucose) and impaired renal function?

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Differential Diagnosis

  • Single Most Likely Diagnosis
    • Diabetes Mellitus: The presence of glucose in the urine (>500) and elevated blood glucose (269) strongly suggests diabetes mellitus. The patient's enlarged, fatty liver is also consistent with this diagnosis, as insulin resistance and diabetes can lead to non-alcoholic fatty liver disease.
  • Other Likely Diagnoses
    • Urinary Tract Infection (UTI): Although the CT scan did not show any urinary tract stones, the presence of blood, WBCs, RBCs, and bacteria in the urine suggests a possible UTI. The patient's diabetes also increases their risk of developing a UTI.
    • Dehydration: The elevated BUN/creatinine ratio (30.7) may indicate dehydration, which is a common complication of diabetes, especially if the patient is not managing their condition properly.
  • Do Not Miss Diagnoses
    • Sepsis: Although the CBC is unremarkable, the presence of bacteria in the urine and the patient's diabetes increase their risk of developing sepsis. Sepsis is a life-threatening condition that requires prompt recognition and treatment.
    • Pyonephrosis: The presence of bacteria, WBCs, and RBCs in the urine, along with the patient's diabetes, increases the risk of pyonephrosis, a serious infection of the kidney that can be life-threatening if not treated promptly.
  • Rare Diagnoses
    • Renal Tubular Acidosis: The presence of glucose in the urine and the elevated BUN/creatinine ratio may suggest renal tubular acidosis, a rare condition characterized by impaired renal acidification.
    • Glucosuria due to other causes: Although diabetes is the most likely cause of glucosuria, other rare conditions such as renal glyaporationing, Fanconi syndrome, or cystic fibrosis can also cause glucose to appear in the urine.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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