Can nattokinase protect against cannabis-associated myocardial infarction and cerebrovascular accident risk?

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Last updated: February 11, 2025View editorial policy

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From the Research

Cannabis-Associated Myocardial Infarction and Cerebrovascular Accident Risk

  • Cannabis use has been linked to an increased risk of myocardial infarction (MI) and cerebrovascular accidents, including ischemic and hemorrhagic stroke 1, 2, 3, 4.
  • The underlying mechanisms of cannabis-associated MI and cerebrovascular accidents are not fully understood, but may involve modulation of adipocyte biology, regional fat distribution, and atherosclerosis, as well as precipitation of hemodynamic stressors 1.
  • Cannabis use has been shown to increase heart rate and blood pressure, and may also cause vascular inflammation, platelet activation, and carboxyhemoglobin generation, which may contribute to the increased risk of MI and cerebrovascular accidents 3.

Nattokinase and Cardiovascular Health

  • There is no direct evidence in the provided studies to suggest that nattokinase can protect against cannabis-associated MI and cerebrovascular accident risk.
  • However, nattokinase has been shown to have fibrinolytic and anticoagulant properties, which may help to reduce the risk of thrombotic events, including MI and stroke 5.

Limitations and Future Directions

  • The current evidence on the relationship between cannabis use and MI and cerebrovascular accidents is largely based on observational studies and case reports, and more research is needed to fully understand the underlying mechanisms and to develop effective prevention and treatment strategies 1, 2, 3, 4.
  • Further studies are also needed to investigate the potential benefits and risks of nattokinase in reducing the risk of MI and cerebrovascular accidents in cannabis users.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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