What are the recommended treatments for back pain?

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Last updated: November 4, 2025View editorial policy

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Back Pain Treatment

For acute low back pain (<4 weeks), start with reassurance about favorable prognosis, advise remaining active, and use NSAIDs or acetaminophen as first-line medication, adding superficial heat and considering spinal manipulation if needed. 1

Initial Assessment

Classify back pain into three categories:

  • Nonspecific mechanical low back pain (most common)
  • Pain potentially associated with radiculopathy or spinal stenosis
  • Pain potentially associated with another specific spinal cause 1

Avoid routine imaging for nonspecific low back pain. 1 Only obtain MRI or CT when severe/progressive neurologic deficits are present, serious underlying conditions are suspected (red flags), or for persistent symptoms in surgical candidates. 1

Screen for psychosocial risk factors that predict progression to chronic disability, as these commonly coexist with back pain. 1

Treatment Algorithm by Duration

Acute Low Back Pain (<4 weeks)

Pharmacologic approach:

  • First-line: NSAIDs (e.g., ibuprofen) or acetaminophen (up to 3000mg/day) 1
  • Avoid systemic corticosteroids - they show no greater efficacy than placebo 1
  • Consider short-term muscle relaxants (cyclobenzaprine 5-10mg) for muscle spasm, though evidence is limited and drowsiness is common 2

Nonpharmacologic approach:

  • Superficial heat application shows good evidence for moderate benefits 1
  • Spinal manipulation demonstrates small to moderate benefits 3, 1
  • Advise patients to remain active and avoid bed rest 1
  • Supervised exercise therapy is NOT effective for acute low back pain 3

Subacute Low Back Pain (4-12 weeks)

Continue first-line approaches if helpful, then add:

  • Intensive interdisciplinary rehabilitation (physician consultation coordinated with psychological, physical therapy, social, or vocational intervention) 3, 1
  • Functional restoration with cognitive-behavioral components to reduce work absenteeism 3, 1

Chronic Low Back Pain (>12 weeks)

Pharmacologic approach:

  • Continue NSAIDs or acetaminophen if effective 1
  • Add tricyclic antidepressants or SNRIs (duloxetine) as part of multimodal strategy 3, 1
  • For radicular symptoms: Consider gabapentin (titrated to 1200-3600mg/day), though benefits are small and short-term 1, 4
  • Avoid extended medication courses unless patients show continued benefits without major adverse events 3

Nonpharmacologic approach (all have moderate evidence):

  • Exercise therapy - cornerstone of treatment, particularly programs with individual tailoring, supervision, stretching, and strengthening 3, 1
  • Cognitive-behavioral therapy 3, 1
  • Spinal manipulation 3, 1
  • Massage therapy 3, 1
  • Acupuncture 3, 1
  • Yoga (Viniyoga-style) 3, 1
  • Intensive interdisciplinary rehabilitation 3, 1

Special Considerations for Radiculopathy

For radicular pain, use a combined approach:

  • NSAIDs (naproxen) target the inflammatory component 4
  • Gabapentin addresses the neuropathic component 4
  • Note: Lumbosacral radiculopathy is relatively refractory to existing medications 4

Avoid continuous or intermittent traction - it has not shown effectiveness for radicular symptoms 3, 1

Consider MRI and specialist referral if radicular symptoms persist beyond 4 weeks despite conservative management 1

Common Pitfalls to Avoid

Imaging overuse: MRI/CT findings are often nonspecific and do not improve outcomes in nonspecific low back pain 1

Medication misuse:

  • Avoid overreliance on opioids - reserve only for time-limited courses when clearly beneficial 3
  • Avoid benzodiazepines without time limitations 3
  • Avoid systemic corticosteroids - they lack efficacy evidence 1

Ineffective treatments to avoid:

  • Transcutaneous electrical nerve stimulation (TENS) - not proven effective 3
  • Continuous or intermittent traction - not effective even with sciatica 3, 1
  • Supervised exercise for acute low back pain 3

Medication Dosing Specifics

Cyclobenzaprine (if used for muscle spasm):

  • Start with 5mg three times daily, may increase to 10mg three times daily 2
  • Use caution in elderly - start with 5mg and titrate slowly 2
  • Limit to short-term use (evidence supports 7-day courses) 2
  • Combination with naproxen increases drowsiness 2

Gabapentin (for radicular pain):

  • Titrate to 1200-3600mg/day 4
  • Use lower starting doses and gradual titration in elderly 4
  • Time-limited course recommended 4

References

Guideline

Guidelines for Managing Back Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Gabapentin for Spinal Stenosis Pain and Radiculopathy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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