From the Research
Blastocystis hominis can potentially cause severe fatigue symptoms in some individuals, though the evidence is mixed and treatment should only be considered when symptoms are present and other causes have been ruled out. This microscopic parasite commonly inhabits the digestive tract and while many people carry it without symptoms, others may experience fatigue along with gastrointestinal issues like diarrhea, abdominal pain, and bloating. The connection between Blastocystis and fatigue isn't fully established, as it's often difficult to determine whether the parasite is causing symptoms or merely present alongside another condition. Some studies, such as 1, suggest that treatment with antiparasitic medications like metronidazole or Saccharomyces boulardii may be beneficial in reducing symptoms, including fatigue, in patients with Blastocystis hominis infection. However, other studies, like 2, found that patients with Blastocystis hominis improved without specific treatment, making it challenging to determine the clinical significance of this parasite. If you're experiencing severe fatigue and tests show Blastocystis hominis, treatment with metronidazole (500-750 mg three times daily for 7-10 days) or other antiparasitic medications may be considered, but only after other causes of fatigue have been ruled out. It's essential to consult a healthcare provider for proper diagnosis through stool testing and appropriate treatment recommendations, as the fatigue may result from the body's immune response to the parasite or from nutritional deficiencies caused by digestive disturbances 3, 4, 5.