What is the composition of Dymox (amoxicillin)?

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Dymox Composition

Dymox contains amoxicillin as its active ingredient, a semisynthetic aminopenicillin β-lactam antibiotic. 1

Active Pharmaceutical Ingredient

  • Chemical composition: Amoxicillin is chemically designated as (2S,5R,6R)-6-[(R)-(-)-2-amino-2-(p-hydroxyphenyl)acetamido]-3-3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate 1

  • Molecular formula: C₁₆H₁₉N₃O₅S·3H₂O with a molecular weight of 419.45 1

  • Drug class: Semisynthetic penicillin analog of ampicillin with broad-spectrum bactericidal activity against many Gram-positive and Gram-negative microorganisms 1, 2

Available Formulations

Oral suspension formulations (when reconstituted):

  • 125 mg/5 mL suspension: Contains 125 mg amoxicillin as trihydrate per 5 mL, with 0.11 mEq (2.51 mg) sodium per 5 mL 1

  • 250 mg/5 mL suspension: Contains 250 mg amoxicillin as trihydrate per 5 mL, with 0.15 mEq (3.36 mg) sodium per 5 mL 1

Inactive Ingredients

The oral suspension formulations contain the following inactive excipients 1:

  • Microcrystalline cellulose
  • Carboxymethylcellulose sodium
  • Sucrose
  • Colloidal silicon dioxide
  • Sodium citrate
  • Sodium propionate
  • Artificial cream flavor
  • FD&C Red #40
  • FD&C Yellow #6

Mechanism of Action

  • Bactericidal activity: Amoxicillin inhibits bacterial cell wall synthesis, leading to bacterial autolysis 3, 1

  • Antimicrobial spectrum: Active against Gram-positive cocci (including Streptococcus pneumoniae, Streptococcus pyogenes, and methicillin-sensitive Staphylococcus aureus) and select Gram-negative organisms (including Haemophilus influenzae, Escherichia coli, and Proteus mirabilis) 2, 4

  • β-lactamase susceptibility: Amoxicillin alone is inactivated by β-lactamase-producing bacteria; combination with clavulanic acid (as in amoxicillin-clavulanate, not Dymox) extends activity against β-lactamase producers 3, 5

References

Research

Amoxicillin: in vitro and pharmacological studies.

Antimicrobial agents and chemotherapy, 1972

Guideline

Amoxicilina y Amoxicilina-Clavulánico

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Introduction: historical perspective and development of amoxicillin/clavulanate.

International journal of antimicrobial agents, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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