What dermatological manifestations are associated with Myasthenia Gravis (MG)?

Myasthenia gravis is not typically associated with specific dermatological manifestations as a direct part of the disease process. Myasthenia gravis is an autoimmune neuromuscular disorder characterized by weakness and fatigue of voluntary muscles, particularly those controlling eye movements, facial expressions, chewing, swallowing, and breathing. The primary pathophysiology involves antibodies that block or destroy acetylcholine receptors at the neuromuscular junction, preventing proper muscle contraction. However, patients with myasthenia gravis may develop skin conditions related to immunosuppressive treatments used to manage the disease, such as corticosteroids (which can cause acne, skin thinning, and easy bruising) or other immunosuppressants (which may increase risk of infections or skin cancers). Additionally, since myasthenia gravis is an autoimmune condition, patients may have higher rates of comorbid autoimmune disorders that do have dermatological manifestations, such as lupus, dermatomyositis, or pemphigus. If a patient with myasthenia gravis develops skin problems, they should be evaluated to determine whether these are treatment-related side effects or possibly a separate autoimmune condition requiring specific management.