What is the recommended injection site for a flu shot in a 4-year-old child?

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Last updated: November 5, 2025View editorial policy

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Recommended Injection Site for Flu Shot in 4-Year-Olds

For a 4-year-old child, the flu shot should be administered intramuscularly in the deltoid muscle of the upper arm. 1

Site Selection by Age

At 4 years of age, children have transitioned from the infant/toddler injection site recommendations:

  • Children ≥4 years: The deltoid muscle is the preferred site for intramuscular influenza vaccination 1
  • Infants and young children <4 years: The anterolateral aspect of the thigh is preferred 1

The ACIP guidelines consistently specify that for "adults and older children, the deltoid is the preferred site," while "infants and younger children should be vaccinated in the anterolateral thigh." 1 The age cutoff where deltoid becomes preferred is at 4 years of age. 1

Dosing Considerations for 4-Year-Olds

  • Dose volume: 0.5 mL per dose for all children ≥36 months (≥3 years) 1
  • Number of doses: Most 4-year-olds will require only 1 dose per season, unless they are receiving their first-ever influenza vaccine and have never been vaccinated before, in which case 2 doses given ≥4 weeks apart are needed 1

Administration Technique

  • Needle insertion: Administer at a 90-degree angle into the deltoid muscle 1
  • Site preparation: Clean the injection site with an alcohol swab before administration 2
  • Aspiration: Not required for vaccine administration at recommended injection sites, as no large blood vessels exist at these anatomically safe locations 3

Common Pitfall to Avoid

The most critical error would be continuing to use the anterolateral thigh site in a 4-year-old. While this was the correct site when the child was younger, the deltoid muscle is now sufficiently developed and is the guideline-recommended site at this age. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Recommended Injection Site for Fluzone in Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Aspiration in Intramuscular Injections

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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