What is the recommended dose of Betahistine (Serc) for vertigo?
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Dainyal Siddiqui, MD
Internal Medicine
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Manuel Jimenez, MD
Cardiology
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Franz Pierre-Louis, MD
Infectious Disease
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Last updated: March 28, 2025 • View editorial policy
Serc (betahistine) is typically prescribed at a dose of 16 mg three times daily for vertigo, particularly for Meniere's disease and other vestibular disorders. Treatment usually begins at this standard dose, though some patients may start with 8 mg three times daily and increase as needed. The medication should be taken with food to minimize stomach upset. Treatment duration varies depending on response, but often continues for several months, with some patients requiring long-term therapy. Betahistine works by improving blood flow in the inner ear and regulating the vestibular system, which helps reduce vertigo episodes, dizziness, tinnitus, and hearing loss associated with inner ear disorders. Side effects are generally mild and may include headache, upset stomach, or rash. Patients should consult their healthcare provider before starting Serc, especially if they have asthma, peptic ulcer, or pheochromocytoma, as these conditions may be contraindicated.
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