Hepatic Angioembolization for Liver Trauma
Angioembolization (AG/AE) should be considered as a first-line intervention in hemodynamically stable patients with arterial blush on CT scan, and is a critical tool for controlling persistent arterial bleeding after damage control procedures. 1
Initial Assessment and Patient Selection
The treatment approach depends entirely on hemodynamic status at presentation:
- Hemodynamically stable patients with arterial blush (contrast extravasation) on CT scan should undergo AG/AE as first-line therapy 1
- Hemodynamically unstable patients require immediate operative management; AG/AE serves as an adjunct for persistent arterial bleeding after surgical hemostasis or damage control procedures 1
- CT scan with intravenous contrast is mandatory before considering AG/AE to identify arterial injury 1
Indications for Angioembolization
Primary Indications (First-Line)
- Hemodynamically stable patients with arterial blush on CT imaging 1
- Delayed hemorrhage without severe hemodynamic compromise 1
- Hepatic artery pseudoaneurysm (to prevent rupture) 1
Secondary Indications (Adjunctive)
- Persistent arterial bleeding after non-hemostatic or damage control surgical procedures 1
- Post-operative bleeding following hepatic artery ligation or vascular repair 1
- Hemobilia from traumatic false aneurysm 2
Technical Procedure
The embolization procedure involves selective catheterization of the bleeding hepatic artery branch with directed embolic material to obliterate the bleeding source while preserving maximal hepatic perfusion. 3
- Immediate angiography should be performed once HAT or arterial injury is diagnosed 4
- Selective embolization of the specific bleeding vessel is preferred over proximal hepatic artery occlusion 3
- Success rate for hemorrhage control is approximately 83% 5
Critical Timing Considerations
Early angioembolization (performed immediately upon diagnosis) demonstrates superior outcomes compared to delayed intervention:
- Early AG/AE shows trends toward lower mortality (0% vs 50% for late intervention) 5
- Early AG/AE reduces packed red blood cell transfusion requirements 5
- Early AG/AE decreases the number of subsequent liver-related operations 5
Post-Embolization Management
Monitoring Requirements
- Serial clinical evaluations with physical exams and laboratory testing to detect status changes 1
- Monitor for complications including hepatic necrosis, biloma, and abscess formation (increased risk after arterial ligation) 1
- Watch for rebound thrombosis (occurs in approximately 28.6% of cases) 4
Complication Management
- Intrahepatic abscesses: percutaneous drainage 1
- Symptomatic or infected bilomas: percutaneous drainage 1
- Post-traumatic biliary complications: combination of percutaneous drainage and endoscopic techniques 1
Special Considerations
When AG/AE Should NOT Be First-Line
- Hemodynamically unstable patients require immediate operative management 1
- In hemodynamically stable children, contrast blush is not an absolute indication for AG/AE 1
- Patients with multiple organ injuries requiring surgery should undergo operative management 1
Adjunctive Measures
- If AG/AE fails or is unavailable, REBOA may be used as a bridge to definitive hemorrhage control in unstable patients 1
- Cholecystectomy should be performed if right or common hepatic artery ligation is required to prevent gallbladder necrosis 1
Anticoagulation Considerations
- For patients requiring anticoagulation (e.g., pulmonary embolism), antithrombotic therapy can be safely initiated approximately 72 hours after definitive surgical hemostasis 6
- LMWH-based prophylaxis should be started as soon as possible following trauma and may be safe in selected patients with liver injury treated non-operatively 1
Common Pitfalls to Avoid
- Do not delay AG/AE in stable patients with arterial blush—early intervention reduces transfusion requirements and subsequent operations 5
- Do not attempt AG/AE in unstable patients—these patients require immediate operative control 1
- Do not overlook post-embolization complications—hepatic necrosis, biloma, and abscess formation require vigilant monitoring 1
- Do not perform proximal hepatic artery ligation without considering post-operative AG/AE—this combination reduces complications while maintaining hemorrhage control 1