What is the dosage of erythromycin (antibiotic ointment) for a stye?

Erythromycin Ointment Dosing for Stye

Apply erythromycin 0.5% ophthalmic ointment to the affected eyelid margin one or more times daily or at bedtime, continuing for a few weeks based on clinical response. 1

Application Instructions

• Apply directly to the eyelid margin where the stye is located, using a thin ribbon of ointment 1
• Frequency: Once daily (typically at bedtime) or up to multiple times daily depending on severity 1
• Duration: Continue for several weeks, adjusting based on symptom improvement and clinical response 1
• If using fingertips for application, wash hands thoroughly after each use 2

Adjunctive Treatment

• Warm compresses are essential and should be used as standard therapy alongside antibiotic ointment 1
• The combination of warm compresses with topical antibiotics provides symptomatic relief and decreases bacterial load from the eyelid margin 1

Alternative Topical Options

• Bacitracin ointment can be substituted with similar application patterns if erythromycin is unavailable or not tolerated 1

Important Clinical Considerations

• For recurrent styes: Consider underlying staphylococcal blepharitis or meibomian gland dysfunction, which requires more comprehensive eyelid hygiene measures beyond simple antibiotic application 1
• Prevent resistance: If treatment requires repetition, consider intermittent courses using different antibiotics with different mechanisms of action to avoid developing resistant organisms 1
• The typical concentration used is 0.5% erythromycin ophthalmic ointment, which is the standard formulation for ocular use 3

Common Pitfalls to Avoid

• Inadequate treatment duration—continue for the full recommended period even if symptoms improve earlier 1
• Failing to address underlying eyelid hygiene issues in recurrent cases 1
• Not combining with warm compresses, which are a critical component of effective stye management 1