What is Concerta (Methylphenidate)?

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Last updated: March 28, 2025View editorial policy

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From the Guidelines

Concerta is a brand name for methylphenidate, a central nervous system stimulant medication primarily used to treat attention deficit hyperactivity disorder (ADHD) in children and adults, with a mechanism of action involving the reuptake inhibition of dopamine and norepinephrine 1.

Key Characteristics of Concerta

  • It is formulated as an extended-release tablet, typically taken once daily in the morning, with common dosages ranging from 18mg to 72mg depending on age, weight, and response.
  • The medication gradually releases the active ingredient throughout the day, providing symptom control for about 10-12 hours.
  • Side effects may include decreased appetite, sleep difficulties, increased heart rate, and blood pressure, as outlined in the study by 1.

Clinical Considerations

  • Patients should take Concerta exactly as prescribed, avoid crushing or chewing the tablets, and have regular check-ups to monitor effectiveness and side effects.
  • It's essential to note that Concerta is a controlled substance due to its potential for misuse, and it should only be used under medical supervision, as highlighted in the guidelines 1.

Treatment Approach

  • The selection of Concerta as a treatment option should be based on individual patient needs, considering factors such as severity of symptoms, presence of comorbidities, and patient preferences, as recommended by 1.
  • Regular assessment of medication adherence and potential issues in adherence should be discussed openly with patients, and strategies to improve adherence should be implemented, as suggested by 1.

From the FDA Drug Label

Methylphenidate hydrochloride oral solution is a CNS stimulant available as 5 mg/5 mL and 10 mg/5 mL strengths for oral administration. Methylphenidate hydrochloride is a central nervous system (CNS) stimulant. Concerta is another name for Methylphenidate, it is a central nervous system (CNS) stimulant.

  • Key Points:
    • Methylphenidate is used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Narcolepsy.
    • It works by increasing the release of norepinephrine and dopamine into the extraneuronal space.
    • The exact mechanism of action in ADHD is not known 2, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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