Treatment of Furuncles (Boils)
For small furuncles, apply moist heat to promote spontaneous drainage; for large furuncles and all carbuncles, incision and drainage is mandatory, with systemic antibiotics reserved only for cases with fever, extensive surrounding cellulitis, or systemic signs of infection. 1
Initial Treatment Algorithm
Small Furuncles
- Apply moist heat (warm compresses) to promote spontaneous drainage 2, 1
- This conservative approach is satisfactory for small lesions without systemic involvement 2
- No antibiotics are needed for uncomplicated small furuncles 1
Large Furuncles and All Carbuncles
- Incision and drainage is the cornerstone of treatment and is mandatory for all large furuncles and carbuncles 2, 1, 3
- After drainage, cover the surgical site with a dry dressing rather than packing with gauze 1
- Thoroughly evacuate pus and probe to break up any loculations 3
When to Add Systemic Antibiotics
Antibiotics are usually unnecessary after adequate drainage unless specific conditions are present 2, 1. Add systemic antibiotics only when:
- Fever or systemic signs of infection (SIRS criteria: temperature >38°C or <36°C, tachycardia >90 bpm, tachypnea >24/min, WBC >12,000 or <4,000 cells/μL) 1, 4
- Extensive surrounding cellulitis 2, 1, 4
- Multiple lesions present 1, 4
- Markedly impaired host defenses (immunosuppression, diabetes) 1, 4
Antibiotic Selection When Indicated
Choose an agent active against Staphylococcus aureus: 1
- For methicillin-susceptible S. aureus (MSSA): Dicloxacillin 500 mg every 6 hours orally 4
- For suspected or confirmed MRSA (high-prevalence areas or risk factors): Clindamycin 300-450 mg every 6 hours orally 1, 4
- Duration: 5-10 days for mild to moderate infections 4
Common pitfall: Do not treat furuncles or carbuncles with antibiotics alone without drainage—this approach will fail 3
Management of Recurrent Furunculosis
Recurrent furunculosis affects individuals who are often nasal carriers of S. aureus (20-40% of the general population carries the organism) 2. A structured decolonization approach is essential:
Decolonization Protocol
- Intranasal mupirocin ointment twice daily for the first 5 days of each month (reduces recurrences by ~50%) 2, 1
- Daily chlorhexidine body washes during decolonization periods 1
- For more aggressive treatment: Oral clindamycin 150 mg daily for 3 months decreases subsequent infections by ~80% for susceptible strains 2
Environmental and Hygiene Measures
- Thoroughly launder clothing, towels, and bed linens 2, 1
- Use separate towels and washcloths to prevent transmission 2, 1
- Bathe with antibacterial soaps such as chlorhexidine 2
- Decontaminate personal items daily during active infection 1, 4
Family and Close Contact Management
- Screen and treat household members who may be colonized carriers, as outbreaks commonly occur in families and close-contact settings (prisons, sports teams) 2, 5
- Inadequate personal hygiene and exposure to others with furuncles are important predisposing factors 2
Important caveat: Even with optimal decolonization (mupirocin), recurrence reduction is only about 50%, so patient expectations should be managed appropriately 2. The most effective regimen for recurrent cases caused by susceptible organisms is the 3-month clindamycin course 2.