Does high pH water help lower inflammatory markers, such as C-reactive protein (CRP)?

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Last updated: March 28, 2025View editorial policy

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From the Guidelines

There is limited scientific evidence to suggest that high pH (alkaline) water helps lower inflammatory markers, such as C-reactive protein (CRP). While some proponents claim alkaline water can reduce inflammation by neutralizing acid in the body, these claims lack robust scientific support. The human body tightly regulates its pH through multiple systems, primarily the lungs and kidneys, making it difficult for consumed water to significantly alter blood pH or inflammatory status. Some key points to consider:

  • The relationship between dietary components and inflammation is complex, and both essential nutrient deficiencies and excesses can cause inflammation, as noted in a study published in the Annual Review of Nutrition 1.
  • Inflammatory markers, such as CRP, are associated with various chronic diseases, including cardiovascular disease, as discussed in a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association 1.
  • Evidence-based approaches to reducing inflammation include anti-inflammatory diets rich in fruits, vegetables, and omega-3 fatty acids, regular exercise, adequate sleep, stress management, and maintaining a healthy weight.
  • For persistent inflammation concerns, consulting with a healthcare provider is recommended, as they may suggest specific anti-inflammatory medications or supplements based on individual health needs, rather than relying on alkaline water as a primary intervention. It's also important to note that the current evidence on the use of inflammatory markers, such as hs-CRP, in clinical practice is not conclusive, and further research is needed to fully understand their role in cardiovascular disease, as highlighted in studies published in Circulation 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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