Is Remeron (Mirtarmirone, Mirtapine, Mirtazapine) a controlled substance?

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Last updated: March 28, 2025View editorial policy

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From the Research

Remeron (mirtazapine) is not a controlled substance in the United States. It is classified as a tetracyclic antidepressant medication that requires a prescription from a healthcare provider but does not have the additional restrictions associated with controlled substances. Unlike medications such as benzodiazepines, opioids, or stimulants, Remeron has a low potential for abuse and dependence, which is why it is not scheduled under the Controlled Substances Act. This classification means that while you need a doctor's prescription to obtain Remeron, prescriptions can include refills and don't require the special documentation or handling that controlled medications do. However, even though it's not controlled, Remeron should only be taken as prescribed since it can cause side effects like sedation, increased appetite, weight gain, and can interact with other medications. If you're prescribed Remeron, follow your doctor's instructions carefully regarding dosage and timing.

The provided evidence does not directly address the question of whether Remeron is a controlled substance, but it can be inferred that the medication is not scheduled under the Controlled Substances Act due to its low potential for abuse and dependence 1. The studies provided focus on various topics such as hallucinogen drugs, randomized controlled trials, and the efficacy and safety of different medications, but none of them mention Remeron as a controlled substance 2, 3, 4, 5.

Some key points to consider when prescribing Remeron include:

  • Monitoring for side effects such as sedation, increased appetite, and weight gain
  • Interactions with other medications
  • Importance of following the prescribed dosage and timing
  • Potential for dependence and abuse, although considered low

It's essential to prioritize the patient's safety and well-being when prescribing Remeron, and to carefully evaluate the potential benefits and risks of the medication. By doing so, healthcare providers can ensure that patients receive the most effective treatment while minimizing the risk of adverse effects.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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