Management of Mumps
Mumps management is primarily supportive care with isolation, as there is no specific antiviral therapy available; treatment focuses on symptom relief, monitoring for complications, and preventing transmission through droplet precautions. 1, 2, 3
Acute Management of Active Infection
Supportive Care Measures
- Provide adequate hydration and pain control with acetaminophen or NSAIDs for fever and parotid pain 4, 2
- Encourage oral fluid intake to maintain hydration, particularly important given painful swallowing 2
- Apply warm or cold compresses to swollen parotid glands for symptomatic relief 3
- Recommend soft foods and avoidance of acidic foods/beverages that stimulate salivary flow and increase pain 3
Isolation and Infection Control
- Implement droplet precautions and isolate patients for 5 days after onset of parotitis to prevent transmission 4, 3
- Patients are contagious from approximately 7 days before through 8 days after parotid gland swelling onset 1
- Healthcare personnel should use appropriate personal protective equipment when caring for suspected or confirmed cases 3
Monitoring for Complications
Neurological Complications
- Monitor for signs of aseptic meningitis (occurs in 4-6% of clinical cases): severe headache, neck stiffness, photophobia, altered mental status 1, 2
- Watch for meningoencephalitis symptoms, which can cause permanent sequelae including paralysis, seizures, cranial nerve palsies, aqueductal stenosis, and hydrocephalus 1
- If facial droop develops, initiate corticosteroid therapy promptly with prednisone 1-2 mg/kg/day for 5-7 days followed by a taper over 5-7 days to reduce inflammation and improve nerve function 4
- Provide eye protection if facial weakness prevents complete eye closure 4
Gonadal Complications
- In postpubertal males, monitor for orchitis (occurs in up to 38% of cases): testicular pain, swelling, fever 1, 2
- In postpubertal females, assess for oophoritis: lower abdominal pain 1
- Reassure patients that sterility from orchitis occurs only rarely despite the high incidence 5
Other Complications
- Monitor for pancreatitis: severe abdominal pain, nausea, vomiting 1
- Assess for hearing changes, as sensorineural deafness can be sudden in onset, bilateral, and permanent 1, 2
- In pregnant women with first-trimester mumps, counsel about increased risk for fetal death, though mumps is not associated with congenital malformations 5, 1
Diagnostic Confirmation
Laboratory Testing
- Obtain buccal swab around affected parotid gland and Stensen's duct for viral culture or nucleic acid amplification testing (NAAT) 2
- Test for serum mumps IgM antibodies (positive in acute infection) 2
- Consider paired acute and convalescent serum for mumps IgG (4-fold rise indicates recent infection) 2
- The CDC recommends confirming diagnosis through clinical presentation plus laboratory confirmation via virus isolation, significant rise in serum mumps IgG antibody, or positive serologic test for mumps IgM antibody 4
Post-Exposure Management and Prevention
Contact Management
- Identify and vaccinate susceptible contacts to limit spread during outbreaks 4
- Vaccination remains the most effective prevention strategy, with two doses of MMR vaccine providing approximately 88% protection 1, 4
- Routine vaccination has reduced mumps incidence by 99% in the United States since its introduction 1
Reporting Requirements
- Mumps is reportable in most states; follow local public health reporting regulations and procedures 3
- Notify public health authorities promptly to facilitate outbreak investigation and control measures 3
Important Clinical Caveats
- Only 30-40% of mumps infections produce typical acute parotitis; 15-20% are asymptomatic and up to 50% present with nonspecific or respiratory symptoms 5, 1, 2
- Serious complications can occur without evidence of parotitis 5
- Inapparent infection is more common among adults than children, while parotitis occurs more commonly among children aged 2-9 years 5, 1
- Severity of disease generally increases with age, making adult cases particularly important to monitor closely 1
- Complete recovery from facial droop associated with mumps occurs in approximately 70-80% of cases within 3-6 months 4