What are the causes of nocturnal hyperhidrosis (night sweats) during pregnancy?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Night sweats during pregnancy are primarily caused by hormonal fluctuations, particularly increased levels of estrogen and progesterone, as well as physiological changes such as increased blood volume and cardiac output. These hormonal changes affect the body's temperature regulation system, leading to excessive sweating, especially at night 1. Some key factors contributing to nocturnal hyperhidrosis during pregnancy include:

  • Increased blood flow throughout the body, generating more heat
  • Metabolic changes to support the growing baby, producing additional warmth
  • Anxiety and stress, common during pregnancy, triggering the body's fight-or-flight response and causing sweating
  • Potential hypoglycemia (low blood sugar), which may cause night sweats, particularly if meals are skipped It is essential to note that while night sweats are typically normal during pregnancy, they can be a symptom of an underlying condition, such as a cardiovascular disease, which may be affected by the physiological changes during pregnancy, including increases in blood volume and cardiac output, and reductions in systemic vascular resistance and blood pressure 1. To manage night sweats, pregnant women can try wearing lightweight, breathable clothing to bed, keeping their bedroom cool, staying hydrated, using layered bedding for temperature adjustment, and considering a cooling mattress pad. However, if night sweats are accompanied by fever, chest pain, or other concerning symptoms, it is crucial to consult a healthcare provider, as these could indicate an underlying condition requiring medical attention.

From the Research

Nocturnal Hyperhidrosis (Night Sweats) During Pregnancy

  • The exact causes of nocturnal hyperhidrosis during pregnancy are not directly addressed in the provided studies 2, 3, 4, 5, 6.
  • However, study 3 discusses nighttime hot flashes during pregnancy, which may be related to nocturnal hyperhidrosis.
  • The study found that 35% of women reported nighttime hot flashes during pregnancy, and the predictors of these hot flashes included depressive symptoms, low education, and higher body mass index 3.
  • It is possible that similar factors may contribute to nocturnal hyperhidrosis during pregnancy, but further research is needed to confirm this.
  • The other studies provided focus on antibiotic use during pregnancy 2, 4, 5, 6, which may not be directly related to nocturnal hyperhidrosis.
  • Therefore, there is limited evidence to support a specific cause of nocturnal hyperhidrosis during pregnancy, and more research is needed to fully understand this condition.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

A Review of Antibiotic Use in Pregnancy.

Pharmacotherapy, 2015

Research

Pharmacokinetic properties of azithromycin in pregnancy.

Antimicrobial agents and chemotherapy, 2010

Research

Penicillin Allergy Assessment in Pregnancy: Safety and Impact on Antibiotic Use.

The journal of allergy and clinical immunology. In practice, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.