From the Guidelines
Lipton Green Tea works by providing a combination of catechins, particularly (–)-epigallocatechin-3-gallate (EGCG), that inhibit the formation of advanced glycation end-products (AGE) and reduce oxidative stress, thereby potentially reducing the risk of chronic diseases such as diabetes and cardiovascular disease. The mechanism of action of Lipton Green Tea involves the inhibition of AGE formation through the antioxidant properties of its polyphenolic compounds, including EGCG, which has been shown to trap reactive dicarbonyl species such as methylglyoxal (MGO) and glyoxal (GO) 1. Some of the key benefits of Lipton Green Tea include:
- Inhibition of AGE-stimulated gene expression and production of pro-inflammatory cytokines
- Reduction of oxidative stress and inflammation
- Potential reduction in the risk of chronic diseases such as diabetes and cardiovascular disease
- Anticancer and anti-obesity properties The bioactive compounds present in Lipton Green Tea, including EGCG and other catechins, have been shown to be bioavailable and to exert their anti-glycative effects in human subjects after absorption 1. Overall, the consumption of Lipton Green Tea may be a useful strategy for reducing the formation and accumulation of AGE/ALE in the human body and related diseases, due to its high content of anti-AGE compounds such as EGCG 1.
From the Research
Mechanism of Action of Lipton (Green Tea)
The mechanism of action of Lipton (Green Tea) can be understood through its various components and their effects on the body.
- Green tea has been shown to have beneficial effects against a variety of diseases, including cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative diseases 2.
- The major component of green tea, epigallocatechin-3-gallate (EGCG), has been demonstrated to have anti-inflammatory effects by suppressing the gene and/or protein expression of inflammatory cytokines and inflammation-related enzymes 2.
- Green tea and EGCG act as antioxidants to scavenge reactive oxygen species, leading to attenuation of nuclear factor-κB activity, which is a key factor in the inflammatory process 2.
- The consumption of green tea has been correlated with a low incidence of chronic pathologies, such as cardiovascular disease and cancer, in which oxidative stress plays a critical role 3.
- Tea catechins and theaflavins, the bioactive phytochemicals responsible for the antioxidant activity of green tea, have pharmacological activities such as the ability to lower glucose, lipid, and uric acid levels 3.
- Epigallocatechin gallate, the most active compound in green tea, inhibits the enzymes involved in cholesterol and uric acid metabolism, and affects glucose transporters 3.
- Green tea has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies 4.
- Green tea extract has been found to reduce blood pressure, inflammatory biomarkers, and oxidative stress, and improve parameters associated with insulin resistance in obese, hypertensive patients 5.
- The protective effects of green tea on the cardiovascular system are thought to be due to its antioxidative, anti-inflammatory, antiproliferative, and antithrombotic properties, as well as its beneficial effects on endothelial function 6.