What is the diagnosis for a patient with a history of perianal abscess (abscess near the anus) drainage, now presenting with perianal discharge, a cord-like structure on digital rectal examination (DRE), and an internal opening at the dentate line on proctoscopy (examination of the rectum using a proctoscope), without swelling, fever, or leukocytosis (elevated white blood cell count)?

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Diagnosis: Intersphincteric Fistula (Answer C)

This patient has an intersphincteric fistula, characterized by the history of recurrent perianal abscesses, persistent perianal discharge, a palpable cord-like tract on digital rectal examination, and an internal opening at the dentate line without current acute infection.

Clinical Reasoning

Key Diagnostic Features Present

  • Recurrent perianal abscess history: Anorectal abscesses are associated with anal fistulas in approximately one-third of patients, and the majority of anal fistulae arise from preexisting abscesses 1

  • Cord-like structure on DRE: This represents the fibrous fistula tract itself, which develops after the acute abscess has drained 2

  • Internal opening at dentate line: This is the pathognomonic feature of cryptoglandular fistulas, as anal glands lie in the intersphincteric space at the dentate line 3. The presence of an internal opening at the dentate line is specifically used to define and classify fistulas 1

  • Absence of acute infection: No swelling, fever, or leukocytosis indicates this is a chronic fistula rather than an active abscess 1

Anatomical Classification

Intersphincteric fistulas are defined as tracts located between the internal and external sphincter muscles 1. This classification fits the clinical presentation because:

  • The internal opening is at the dentate line (where intersphincteric fistulas originate) 1, 4
  • The palpable cord suggests a tract confined to the intersphincteric plane
  • There is no mention of extension through the external sphincter or into deeper spaces 1

Why Not the Other Options?

Perianal fistula (Option A): While this term is sometimes used generically, in formal classification systems, a perianal abscess is specifically "a simple anorectal abscess" in the subcutaneous tissue, not a fistula tract 1. The presence of a cord-like structure and internal opening indicates a more specific fistula type.

Ischiorectal fistula (Option B): Ischiorectal (ischioanal) abscesses and fistulas penetrate through the external anal sphincter into the ischioanal space 1. This patient's presentation lacks features suggesting extension beyond the sphincter complex into the ischiorectal fossa 1.

Supralevator abscess (Option D): This is clearly incorrect as there is no current abscess (no swelling, fever, or leukocytosis) 1. Additionally, supralevator abscesses are located superior to the intersphincteric plane in the supralevator space and would present with a palpable mass or induration above the levator ani, not a simple cord-like structure 1, 4.

Clinical Pearls

  • Fistula development after abscess drainage: Perianal fistulas can be detected in approximately 50% of cases after drainage of a perianal abscess 3. The two-year history with recurrence strongly suggests fistula formation 1

  • The cryptoglandular hypothesis: The majority of anorectal abscesses and fistulas are idiopathic, with infection of anal glands at the dentate line being the most commonly accepted mechanism 1, 3

  • Importance of internal opening identification: Finding the primary opening at the dentate line is crucial for proper diagnosis and surgical planning 4

Important Caveat

Given the recurrent nature of this patient's abscesses, it is mandatory to exclude underlying Crohn's disease, especially with recurrent presentations 1. A focused medical history should assess for inflammatory bowel disease symptoms, though the classic intersphincteric location with internal opening at the dentate line is consistent with cryptoglandular disease 1.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Fistulas and fissures. Part I: perianal fistulas].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2008

Research

[Anorectal abscess and fistula].

Therapeutische Umschau. Revue therapeutique, 1997

Research

High intermuscular anal abscess and fistula: analysis of 25 cases.

Canadian journal of surgery. Journal canadien de chirurgie, 1983

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