Immediate Treatment for Bell's Palsy
Start oral corticosteroids immediately if the patient presents within 72 hours of symptom onset—this is the only evidence-based treatment that significantly improves facial nerve recovery. 1, 2
First-Line Treatment Protocol
Corticosteroid Regimen (Must Start Within 72 Hours)
- Prednisolone 50 mg daily for 10 days OR Prednisone 60 mg daily for 5 days followed by a 5-day taper 1, 2
- Evidence demonstrates 83% recovery at 3 months with prednisolone versus 63.6% with placebo, and 94.4% recovery at 9 months versus 81.6% with placebo 2
- Treatment initiated beyond 72 hours has unclear benefit and is not supported by high-quality evidence 3
Combination Therapy Consideration
- May add antiviral therapy to corticosteroids within the 72-hour window as an optional enhancement 1
- Valacyclovir 1 g three times daily for 7 days OR Acyclovir 400 mg five times daily for 10 days 4
- Some evidence shows higher complete recovery rates with combination therapy (96.5%) compared to steroids alone (89.7%) 1
- Never use antiviral monotherapy—it is ineffective and not recommended 1, 2, 4
Immediate Eye Protection (Critical for All Patients)
Implement eye protection immediately for any patient with impaired eye closure to prevent corneal damage. 1, 2
Daytime Protection
- Frequent lubricating ophthalmic drops throughout the day 1, 2
- Sunglasses for outdoor protection against foreign particles 1, 2
Nighttime Protection
- Ophthalmic ointments for more effective moisture retention 1, 2
- Eye patching or taping with careful instruction on proper technique to avoid corneal abrasion 1, 2
- Moisture chambers using polyethylene covers 2
Severe Cases Requiring Urgent Ophthalmology Referral
- Eye pain, vision changes, redness, discharge, or foreign body sensation 2
- Consider botulinum toxin injections, tarsorrhaphy, or eyelid weight implantation for persistent severe lagophthalmos 2
Management Algorithm Based on Presentation Timing
Within 72 Hours of Symptom Onset
- Start oral corticosteroids immediately 1, 2
- Consider adding antiviral therapy 1, 4
- Implement eye protection measures 1, 2
- No routine laboratory testing or imaging needed for typical presentations 2
Beyond 72 Hours (Day 5 or Later)
- Do not start corticosteroids—minimal benefit with medication risks 3
- Focus on comprehensive eye protection 3
- Counsel patient that 70% with complete paralysis recover spontaneously within 6 months, and up to 94% with incomplete paralysis recover 3, 4
- Monitor for recovery signs within 2-3 weeks 2
Follow-Up and Referral Criteria
Reassess or refer to a facial nerve specialist if: 1, 2
- New or worsening neurologic findings develop at any point
- Ocular symptoms develop
- Incomplete facial recovery persists 3 months after initial symptom onset
- Atypical features present: bilateral weakness, isolated branch paralysis, other cranial nerve involvement, or recurrence on same side 2
Critical Pitfalls to Avoid
- Delaying treatment beyond 72 hours eliminates the effectiveness of corticosteroid therapy 1, 3
- Using antiviral therapy alone is completely ineffective 1, 2, 4
- Failing to provide adequate eye protection can lead to permanent corneal damage 1, 2
- Improper eye taping technique can cause corneal abrasion—patients must receive careful instruction 2
- Missing atypical features that require imaging to rule out other causes of facial weakness 1, 2
Special Populations
Children
- Higher rates of spontaneous recovery than adults (up to 90%) 4
- Evidence for steroid benefit is less conclusive 1, 2
- Consider treatment on individualized basis with caregiver involvement 2