What is degenerative joint disease of the shoulder?

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What is Degenerative Joint Disease of the Shoulder?

Degenerative joint disease of the shoulder, also called glenohumeral osteoarthritis, is a progressive wearing away of the smooth cartilage that cushions your shoulder joint, leading to bone-on-bone contact, pain, stiffness, and loss of motion. 1, 2

How Your Shoulder Joint Breaks Down

Your shoulder is a ball-and-socket joint where the round top of your arm bone (humeral head) fits into a shallow socket (glenoid). Normally, smooth cartilage covers both surfaces, allowing pain-free movement. 2

In osteoarthritis, this protective cartilage gradually wears away through a process involving:

  • Chronic inflammation inside the joint that releases damaging chemicals and enzymes that break down cartilage 3
  • Loss of the smooth, spherical joint surfaces as the underlying bone begins to remodel abnormally 2
  • Thickening and tightening of the joint capsule (the tissue surrounding your joint), which further restricts your ability to rotate your shoulder 2
  • Progressive destruction of both the humeral head and glenoid surfaces that is irreversible 4

What Causes It

Primary osteoarthritis develops mainly from aging and natural wear-and-tear over time. 5

Secondary osteoarthritis results from specific causes including:

  • Previous shoulder injuries or surgeries 3
  • Chronic overuse from repetitive overhead activities 3
  • Shoulder instability (a loose joint that has dislocated or subluxed repeatedly) 3
  • Old fractures involving the shoulder joint 4

Who Gets It

  • More common in women than men 1
  • Increases with age, affecting up to one-third of people over 60 years old 4
  • Third most common joint requiring replacement surgery after the knee and hip 1

What You'll Experience

Pain is typically:

  • Worse with weight-bearing activities and movement 5
  • Present during overhead activities 2
  • May occur at rest in advanced cases 4

Stiffness manifests as:

  • Difficulty after periods of inactivity 5
  • Progressive loss of shoulder rotation 2
  • Reduced ability to reach overhead or behind your back 4

Loss of function includes:

  • Limitations in daily activities like dressing, grooming, or reaching 4
  • Long-standing history of gradually worsening symptoms 4
  • Possible acute flare-ups of chronic pain 4

Associated problems may involve:

  • Cognitive and psychosocial difficulties from chronic pain 3
  • Inflammation of surrounding soft tissues 4

How It's Diagnosed

Your doctor will identify shoulder arthritis through:

  • Medical history focusing on previous injuries, surgeries, pattern of pain, and functional limitations 2, 4
  • Physical examination checking range of motion, strength, pain with specific movements, and joint stability 2
  • X-rays showing cartilage loss, bone spurs, and joint space narrowing 2, 5
  • CT scan if surgery is being considered, to evaluate bone quality and shape of the socket 3
  • Blood tests only if needed to rule out other types of arthritis causing secondary osteoarthritis 5
  • Joint fluid analysis (arthrocentesis) in select cases to exclude other conditions 5

Treatment Options Available

The American Academy of Orthopaedic Surgeons provides guidance on managing shoulder osteoarthritis, though they acknowledge that evidence for many treatments remains limited. 1

For mild disease:

  • Over-the-counter pain medications like acetaminophen or NSAIDs (ibuprofen, naproxen) 2
  • Physical therapy to maintain motion and strengthen surrounding muscles 1, 2

For moderate disease:

  • Corticosteroid injections into the joint (though evidence is inconclusive) 1
  • Hyaluronic acid injections, which may provide longer-lasting relief than corticosteroids 3

For severe disease refractory to conservative treatment:

  • Total shoulder arthroplasty (replacing both the ball and socket) is moderately recommended over hemiarthroplasty (replacing only the ball) 1
  • Arthroscopic debridement or capsular release for select cases 1, 2
  • Surgery should be performed by experienced surgeons (those doing at least 2 shoulder replacements per year have better outcomes) 1

Important Considerations

Surgery is NOT recommended if:

  • You have an irreparable rotator cuff tear, as this significantly affects outcomes 1

The disease is progressive:

  • Once cartilage is destroyed, it cannot regenerate 4
  • Treatment focuses on symptom management and maintaining function 5
  • Surgical intervention becomes necessary when conservative measures fail to control pain or restore acceptable function 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Shoulder osteoarthritis: diagnosis and management.

American family physician, 2008

Research

A comprehensive approach to glenohumeral arthritis.

Southern medical journal, 2014

Research

Osteoarthritis.

The Journal of the Association of Physicians of India, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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