What is the recommended dose of Mucinex (Guaifenesin) for an 11-year-old?

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Mucinex (Guaifenesin) Dosing for an 11-Year-Old

For an 11-year-old child, the recommended dose of Mucinex (guaifenesin) is 5 to 10 mL (1 to 2 teaspoonfuls or 100-200 mg) every 4 hours for immediate-release formulations, not exceeding 6 doses in 24 hours. 1

Standard Dosing by Age

The FDA-approved dosing for guaifenesin in the pediatric population follows age-based guidelines:

  • Children 6 years to under 12 years: 5 to 10 mL (100-200 mg) every 4 hours 1
  • Children 12 years and over: 10 to 20 mL (200-400 mg) every 4 hours 1
  • Maximum frequency: Do not exceed 6 doses in any 24-hour period 1

Since an 11-year-old falls into the "6 years to under 12 years" category, the appropriate dose is the lower range (100-200 mg every 4 hours). 1

Extended-Release Formulation Considerations

Extended-release guaifenesin (Mucinex ER) is not FDA-approved for children under 12 years of age. 1 The immediate-release formulation requiring dosing every 4 hours is the only appropriate option for this age group. 1

  • Extended-release formulations are designed for 12-hourly dosing in adults and children ≥12 years 2
  • The pharmacokinetic studies establishing bioequivalence and safety of ER formulations were conducted in adult populations 2

Important Clinical Considerations

Guaifenesin functions as an expectorant to help loosen mucus and make coughs more productive, though its mechanism of action involves increasing hydration and decreasing viscosity of respiratory secretions. 3, 4

Common Pitfalls to Avoid:

  • Do not use extended-release formulations in children under 12 years: These have not been studied or approved for this age group and could result in inappropriate dosing 1
  • Avoid exceeding 6 doses per day: This represents the maximum safe dosing frequency for immediate-release guaifenesin 1
  • Do not confuse with combination products: Many OTC products contain guaifenesin plus other active ingredients (dextromethorphan, phenylephrine, etc.) that have different pediatric dosing restrictions 3

Practical Administration:

  • Liquid formulations are preferred for this age group for accurate dosing 1
  • Dosing every 4 hours allows flexibility to titrate based on symptom severity 3
  • Multiple daily doses are necessary to maintain therapeutic effect with immediate-release formulations 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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