What is the recommended approach for the C-EASIE-25 (Clinical Evaluation and Assessment of Stroke Intervention with Efficacy-25) Trial treatment protocol?

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C-EASIE-25 Trial Information Not Available

I was unable to locate any information about a "C-EASIE-25" (Clinical Evaluation and Assessment of Stroke Intervention with Efficacy-25) trial in the provided evidence or in established medical literature.

What the Evidence Contains

The provided evidence includes:

  • Guidelines for carotid stenosis management (both symptomatic and asymptomatic) from the American Heart Association/American Stroke Association 1
  • Recommendations for acute stroke therapy trial design from the Stroke Therapy Academic Industry Roundtable (STAIR) 1
  • Guidelines for intra-arterial cerebral thrombolysis trial design 1
  • Systematic reviews of carotid stenosis management guidelines 1
  • General trial design methodology papers 2, 3, 4, 5

Possible Explanations

This trial name may be:

  • A misremembered or incorrectly stated trial acronym
  • A very recent trial not yet indexed in major databases
  • A trial that was planned but not yet published
  • Confusion with other stroke intervention trials

Similar Established Stroke Trials

If you are seeking information about stroke intervention trials, the evidence references several major trials including:

  • NINDS rt-PA Stroke Trial (thrombolytic therapy within 3 hours) 1
  • PROACT-II (intra-arterial prourokinase within 6 hours) 1
  • SAPPHIRE (carotid artery stenting vs. endarterectomy) 1
  • NASCET (North American Symptomatic Carotid Endarterectomy Trial) 1

Please verify the correct trial name or provide additional context so I can provide accurate, evidence-based recommendations.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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