What is the most common operation type for oesophageal (esophageal) cancer surgery?

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Last updated: November 9, 2025View editorial policy

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Most Common Esophageal Cancer Surgery

The Ivor Lewis esophagogastrectomy is the most frequently used procedure for transthoracic esophagogastrectomy and represents the most common operation type among the standard esophageal cancer surgical approaches. 1

Evidence from Guidelines

The National Comprehensive Cancer Network explicitly states that "Ivor Lewis esophagogastrectomy, the most frequently used procedure for transthoracic esophagogastrectomy" is performed using laparotomy and right thoracotomy, with upper thoracic esophagogastric anastomosis at or above the azygos vein. 1

Standard Surgical Options

The three main approaches for esophageal cancer surgery include:

  • Ivor Lewis esophagogastrectomy: Uses right thoracotomy and laparotomy with intrathoracic anastomosis, representing the most common approach for transthoracic resection 1

  • Transhiatal esophagogastrectomy: Performed through abdominal and cervical incisions without thoracotomy, associated with lower morbidity but less extensive lymphadenectomy 1

  • Thoracoabdominal (left transthoracic) esophagogastrectomy: Uses contiguous abdominal and left thoracic incision, primarily reserved for distal esophageal lesions 1

Clinical Context

The Ivor Lewis procedure is suitable for lesions at any thoracic location, though proximal esophageal margin may be inadequate for tumors in the middle esophagus. 1 The European Society for Medical Oncology confirms that radical transthoracic esophagectomy with en bloc two-field lymphadenectomy is the procedure of choice in fit patients, with the Ivor Lewis approach being the standard for distal tumors. 1

Modern Adaptations

Minimally invasive Ivor Lewis esophagectomy (combining laparoscopy with limited thoracotomy or thoracoscopy) has become increasingly implemented, with three randomized controlled trials demonstrating lower postoperative morbidity, quicker functional recovery, and better quality of life compared to open approaches. 1, 2

Important Caveats

  • While transhiatal esophagectomy offered early survival advantage in population-based studies, long-term survival was not different between surgical approaches 1

  • The choice between approaches depends on tumor location, size, stage, surgeon experience, and patient factors 1

  • For mid and upper esophageal tumors, the McKeown procedure (three-field approach with cervical anastomosis) may be preferred over the standard Ivor Lewis 1

Answer: B. Ivor Lewis oesophagectomy

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Medical Necessity of Procedures for Stage III Esophageal Cancer

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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