What is the management for epistaxis (nosebleed) in pregnancy?

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Management of Epistaxis in Pregnancy

Manage epistaxis in pregnancy using the same first-line conservative measures as in non-pregnant patients: firm sustained compression to the lower third of the nose for 10-15 minutes with the patient sitting upright and head tilted slightly forward, followed by topical vasoconstrictors if bleeding persists. 1, 2, 3

Initial Management Approach

Position and compression are your first interventions:

  • Seat the patient upright with head tilted slightly forward (not backward) to prevent blood from entering the airway or being swallowed 2, 3, 4
  • Apply firm, sustained compression to the soft lower third of the nose (not the nasal bridge) for a full 10-15 minutes without checking if bleeding has stopped 1, 2, 3
  • Have the patient breathe through their mouth and spit out any blood rather than swallowing it 3
  • This simple compression alone stops bleeding in the majority of cases 1, 3

If Bleeding Persists After Compression

Topical vasoconstrictors are the next step:

  • Apply oxymetazoline or phenylephrine spray (2 sprays in the bleeding nostril) after clearing any clots 1, 2, 3
  • This resolves 65-75% of epistaxis cases that don't respond to compression alone 1, 2, 5
  • Vasoconstrictors can be applied on cotton pledgets or as nasal spray 1

Pregnancy-Specific Considerations

Epistaxis is common in pregnancy due to hormonal changes and increased nasal vascularity, but severe cases require heightened vigilance:

  • Mild epistaxis is extremely common in pregnancy and typically responds to conservative measures 6, 7, 8
  • Severe epistaxis in pregnancy may indicate underlying pathology such as nasal pyogenic granuloma (pregnancy tumor), which can cause torrential bleeding 8
  • If bleeding is severe or recurrent despite conservative measures, ENT evaluation is mandatory to exclude nasal lesions like pyogenic granuloma 6, 8
  • Severe cases may require examination under anesthesia and can necessitate delivery for definitive resolution 6, 7

After Bleeding Control

Prevention of recurrence is essential:

  • Apply petroleum jelly or other moisturizing/lubricating agents to the nasal mucosa 1, 2, 3
  • Recommend regular saline nasal sprays to maintain mucosal moisture 2, 3
  • Avoid nasal trauma, nose-picking, and forceful nose-blowing 1

Advanced Interventions if Conservative Measures Fail

Escalate systematically if first-line measures don't work:

  • Nasal packing: If bleeding continues after 15 minutes of compression and vasoconstrictor use, nasal packing is indicated 1, 2, 3
  • Use resorbable packing materials (such as Nasopore, Surgicel, or Floseal) rather than non-resorbable packing to reduce need for removal visits and decrease complications 1, 5
  • Nasal endoscopy: Perform or refer for endoscopy to identify the bleeding site, especially important in pregnancy to rule out lesions like pyogenic granuloma 1, 3, 8
  • Cauterization: If a specific bleeding site is identified, chemical or electrical cautery can be performed 1, 4, 5

When to Seek Immediate Specialist Consultation

Red flags requiring urgent ENT evaluation:

  • Bleeding not controlled after 15 minutes of continuous pressure 2, 3
  • Signs of hemodynamic instability (tachycardia, hypotension, dizziness from blood loss) 2, 4
  • Severe anemia developing from blood loss 6
  • Recurrent or bilateral epistaxis suggesting hereditary hemorrhagic telangiectasia 1
  • Unilateral epistaxis with associated nasal obstruction, facial pain, or visual changes suggesting mass lesion 4

Critical Pitfalls to Avoid

Common errors in epistaxis management:

  • Do not have the patient tilt their head backward - this causes blood to flow into the airway and stomach 2, 3
  • Do not compress the nasal bridge - compression must be applied to the soft lower third of the nose where the bleeding vessels are located 1, 4
  • Do not check if bleeding has stopped before 10-15 minutes - premature release of pressure prevents clot formation 1
  • Do not dismiss severe or recurrent epistaxis in pregnancy - always consider underlying nasal pathology like pyogenic granuloma that may require surgical intervention 6, 8
  • Do not delay ENT consultation for severe cases, as pregnancy-related epistaxis can be life-threatening and may require delivery for resolution 6, 7

Medication Safety

No need to adjust medications for isolated epistaxis:

  • Do not discontinue psychiatric or other medications for a single epistaxis episode 2
  • First-line conservative treatments should be attempted before considering any medication adjustments 2
  • However, document any anticoagulant or antiplatelet use as this increases bleeding risk 1, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Nasal Epistaxis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Epistaxis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Causes and Management of Unilateral Epistaxis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Epistaxis Treatment Options: Literature Review.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2023

Research

Severe epistaxis in pregnancy due to nasal pyogenic granuloma: A case report.

Journal of Taibah University Medical Sciences, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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