Immediate Treatment for Bell's Palsy
Start oral corticosteroids immediately within 72 hours of symptom onset—this is the single most important intervention that significantly improves facial nerve recovery. 1
First-Line Treatment Protocol
Prescribe one of these corticosteroid regimens: 1, 2
- Prednisolone 50 mg daily for 10 days, OR
- Prednisone 60 mg daily for 5 days, then taper by 10 mg daily over the next 5 days 1, 3
The evidence is compelling: 83% of patients recover at 3 months with prednisolone versus only 63.6% with placebo, and 94.4% recover at 9 months versus 81.6% with placebo. 2 Do not delay—treatment effectiveness drops significantly after the 72-hour window. 1
Combination Therapy Consideration
Consider adding antiviral therapy to corticosteroids for potentially better outcomes: 1
While the American Academy of Otolaryngology-Head and Neck Surgery states combination therapy "may be considered as an option," the research evidence shows higher complete recovery rates with combination therapy (96.5%) compared to steroids alone (89.7%). 1 One study demonstrated 87.5% complete recovery with valacyclovir plus prednisone versus 68% with no treatment, with particularly pronounced benefits in elderly patients (100% recovery in treated patients over 60 versus 42% in untreated). 4
Critical caveat: Never use antiviral monotherapy—it is ineffective and explicitly not recommended. 1, 3
Immediate Eye Protection
Implement eye protection measures immediately for any patient with impaired eye closure: 1, 2
- Lubricating ophthalmic drops frequently throughout the day 2
- Ophthalmic ointment at bedtime (more effective moisture retention but causes temporary vision blurring) 2
- Eye patching or taping at night (requires careful instruction on proper technique to avoid corneal abrasion) 2
- Sunglasses for outdoor protection 2
- Moisture chambers using polyethylene covers for nighttime 2
Failure to provide adequate eye protection can lead to corneal damage and is a common pitfall. 1
Age-Specific Considerations
For patients 16 years and older: Use the full corticosteroid regimen as outlined above. 1, 2
For children: Evidence for steroid benefit is less conclusive as children show higher spontaneous recovery rates (up to 90%). 2, 3 Consider oral steroids on an individualized basis with caregiver involvement. 2
For pregnant women: Treat with oral corticosteroids on an individualized basis with careful assessment of benefits versus risks. 2 Combination therapy with antivirals may also be considered individually. 2
What NOT to Do
Avoid these critical errors: 1, 2
- Do not delay treatment beyond 72 hours—effectiveness drops significantly 1
- Do not prescribe antiviral monotherapy—it is ineffective 1, 3
- Do not order routine laboratory testing or imaging for typical presentations 1, 2
- Do not fail to provide eye protection for patients with impaired eye closure 1
- Do not diagnose Bell's palsy without ruling out other causes of facial weakness through thorough history and physical examination 1
When to Reassess or Refer
Reassess or refer to a facial nerve specialist if: 1, 2
- New or worsening neurologic findings develop at any point
- Ocular symptoms develop
- Incomplete facial recovery persists 3 months after initial symptom onset
Algorithm Summary
- Confirm diagnosis through history and physical examination (acute unilateral facial weakness involving forehead, onset <72 hours, no other identifiable cause) 2
- Start corticosteroids immediately if within 72-hour window 1, 2
- Add antiviral therapy for potentially better outcomes, especially in severe cases 1, 3, 4
- Implement eye protection immediately if impaired eye closure present 1, 2
- Schedule follow-up at 3 months to assess recovery 1, 2