Initial Management of Trauma Patients
The initial management of trauma patients must follow a systematic, prioritized approach beginning with immediate assessment of hemodynamic stability, airway control, and rapid identification of life-threatening injuries through clinical examination and focused imaging, with all interventions aimed at early hemorrhage control and prevention of secondary injury. 1
Immediate Assessment and Stabilization
Hemodynamic Status Assessment
- Assess hemodynamic stability immediately upon patient contact, defined as systolic blood pressure ≥90 mmHg and heart rate 50-110 beats per minute 1
- Evaluate mechanism of injury to identify patients at risk for significant traumatic hemorrhage 1, 2
- Use serum lactate or base deficit measurements to estimate and monitor the extent of bleeding and shock 1
Airway Management (First Priority)
- Secure the airway immediately in patients with apnea, gasping breathing (respiratory rate <6/min), hypoxia (SpO2 <90% despite oxygen), severe traumatic brain injury (GCS <9), hemodynamic instability (SBP <90 mmHg), or severe chest trauma with respiratory insufficiency (respiratory rate >29/min) 3
- Perform endotracheal intubation via the oral route using rapid sequence induction with manual in-line cervical spine stabilization 4, 3
- Use ketamine as the preferred induction agent; avoid etomidate due to adrenal suppression 3
- Confirm tube placement with capnography, which is absolutely mandatory 3
- Have alternative airway devices immediately available; consider alternative methods after maximum three unsuccessful intubation attempts 3
Ventilation Strategy
- Apply initial normoventilation unless signs of imminent cerebral herniation are present 1
- For suspected brain herniation: temporarily hyperventilate to PaCO2 30-35 mmHg as a temporizing measure only 5
- Maintain PaO2 between 60-100 mmHg 5
- Avoid prolonged hyperventilation beyond a few hours due to risk of cerebral ischemia 5
Hemorrhage Control Measures
Prehospital Interventions
- Apply tourniquets immediately for life-threatening bleeding from open extremity injuries 1
- Apply external pelvic compression as soon as possible in all patients with suspected severe pelvic trauma 1, 2
- Use pelvic binders (not sheet wrapping) placed around the greater trochanters 1, 2
- Transport all severe trauma patients directly to a designated trauma center 1, 2
Physical Examination
- Inspect the abdomen for distension, asymmetry, laceraciones, abrasions, and "seat belt sign" which alert to possible intra-abdominal injury 2
- Assess for significant abdominal rigidity and involuntary guarding, which indicate peritonitis and suggest intestinal content leakage 2
Diagnostic Imaging Strategy
For Hemodynamically Unstable Patients
- Perform portable chest and pelvic radiographs immediately upon arrival 1, 2
- Perform Extended Focused Assessment with Sonography for Trauma (E-FAST) at bedside 1
- E-FAST has 97% positive predictive value for intra-abdominal bleeding in pelvic trauma with associated abdominal trauma 1
- E-FAST findings of hemopericardium, pneumothorax, or free intraperitoneal fluid have significant implications for immediate surgical intervention 1
- Proceed directly to operative intervention for bleeding control without CT imaging in most cases 1
- Consider whole-body CT only if degree of instability is mild and CT scanner is immediately accessible, as this may help determine optimal surgical approach 1
For Hemodynamically Stable Patients
- Perform CT of chest, abdomen, and pelvis with IV contrast 1, 2
- Use early imaging (ultrasonography or CT) to detect free fluid in suspected torso trauma 1
- Contrast-enhanced CT with multiplanar reformations is the standard imaging tool due to fast acquisition and excellent resolution 1
- Multiphasic protocols with arterial phase improve identification of vascular injuries; portal venous phase is best for solid organ assessment 1
Coagulation Management
Monitoring
- Perform early, repeated, combined measurement of PT, APTT, fibrinogen, and platelets to detect post-traumatic coagulopathy 1
- Use viscoelastic testing to characterize coagulopathy and guide hemostatic therapy 1
- Do not rely on single hematocrit measurements as an isolated marker for bleeding 1
Resuscitation Strategy
- Initiate early and aggressive hemostatic resuscitation with prompt diagnosis of life-threatening injuries and early control of ongoing bleeding 1
- Maintain systolic blood pressure >100 mmHg or mean arterial pressure >80 mmHg to ensure adequate cerebral perfusion 5
- Avoid excessive fluid restriction, which causes hypotension and reduced cerebral perfusion 5
Critical Pitfalls to Avoid
- Do not delay intervention in hemodynamically unstable patients with identified bleeding source; proceed immediately to bleeding control 1
- Intestinal injury remains one of the most commonly missed injuries on initial CT (20% undetected), requiring serial examinations 2
- Do not perform CT imaging without IV contrast in trauma patients; contrast administration is essential 1
- Avoid prolonged hyperventilation, which can cause cerebral ischemia 5
- Do not delay osmotherapy while waiting for neuroimaging in patients with clear signs of brain herniation 5
Institutional Protocol Requirements
Each institution must implement an evidence-based treatment algorithm for bleeding trauma patients with treatment checklists to guide clinical management and routine quality assessment of adherence 1