From the Research
There are no significant contraindications between Keppra (levetiracetam) and Viagra (sildenafil), and they can generally be taken together safely as they work through different mechanisms in the body and have minimal interaction potential. Keppra is an antiepileptic medication that works by modulating neurotransmitter release in the brain, while Viagra is a phosphodiesterase type 5 (PDE5) inhibitor that increases blood flow to the penis by relaxing blood vessels. According to a study published in 2018 1, levetiracetam has no significant effect on sexual function and sex hormones, which supports the safety of combining it with sildenafil.
Some key points to consider when taking these medications together include:
- Monitoring for unusual side effects, as both medications can occasionally cause dizziness or fatigue, which might be additive when taking both drugs.
- Informing your healthcare provider about all medications you're taking, including over-the-counter drugs and supplements, to ensure comprehensive medication management.
- Being aware of the potential for decreased libido or other sexual dysfunction related to antiepileptic drugs, as discussed in a review published in 2016 2 and a study published in 2017 3.
- Understanding that the semen quality of males with epilepsy may be decreased even before treatment, as found in a study published in 2018 1.
Overall, the combination of Keppra and Viagra is considered safe, but it's essential to be aware of potential side effects and to monitor your health closely while taking these medications together.