What are the patient instructions for using Dovobet (calcipotriol and betamethasone) for treating psoriasis plaques on the scalp?

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Last updated: November 10, 2025View editorial policy

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Patient Instructions for Dovobet (Calcipotriene/Betamethasone) for Scalp Psoriasis

Apply Dovobet once daily to scalp psoriasis plaques for 4-8 weeks, carefully parting the hair and applying only to affected areas while avoiding the forehead and face. 1, 2

Application Technique

  • Comb your hair first to remove any scaly debris before applying the medication 2
  • Part your hair in sections to expose the psoriasis plaques on your scalp 2
  • Apply the medication only to the affected areas (the psoriasis plaques), not to healthy scalp 2
  • Rub in gently and completely until absorbed 2
  • Avoid spreading the solution onto your forehead or face during application 2
  • Always wash your hands thoroughly immediately after each application 2

Dosing Schedule

  • Use once daily for optimal results 1, 3, 4
  • Continue treatment for 4-8 weeks as this is the timeframe where efficacy has been demonstrated 1, 2
  • You can expect approximately 69-74% chance of achieving clear or almost clear scalp with consistent use 1

Critical Safety Warnings

  • Keep the medication away from your eyes at all times 2
  • Do not exceed 100 grams per week in adults to prevent calcium elevation in your blood 5, 1
  • Never use salicylic acid products at the same time as Dovobet, as the acid will inactivate the calcipotriene component and make it ineffective 1, 6
  • Avoid excessive sun exposure (including tanning beds and sun lamps) on treated areas, as this medication may increase sensitivity to UV light 2

What to Watch For

  • Mild irritation of the treated skin or surrounding areas is common and usually temporary 5
  • Stop using the medication and contact your doctor if you develop significant irritation 2
  • Report any adverse reactions to your healthcare provider 2
  • If you need phototherapy (light treatment), apply Dovobet after the UV treatment, not before 6

Important Limitations

  • This medication is for external use only - do not ingest 2
  • Use only for psoriasis as prescribed by your physician, not for other skin conditions 2
  • Avoid applying to uninvolved scalp margins (healthy skin around the plaques) 2
  • Do not use during pregnancy unless specifically directed by your doctor, as it is Category C 5

Storage and Handling

  • Keep out of reach of children 2
  • Store according to package instructions
  • The gel formulation was specifically developed for scalp psoriasis and may be easier to apply than ointment 3, 4

References

Guideline

Scalp Psoriasis Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Calcipotriene Treatment for Psoriasis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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