What is the cause of death?

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Last updated: March 29, 2025View editorial policy

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From the Guidelines

Cardiovascular disease is the single most important cause of death for both men and women. This is based on the most recent and highest quality evidence available, which emphasizes the significance of cardiovascular disease as a leading cause of mortality 1.

Key Points to Consider

  • The study published in the European Heart Journal in 2012 highlights the importance of cardiovascular disease prevention in clinical practice 1.
  • The fifth joint task force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice constituted by representatives of nine societies and by invited experts, further solidifies the evidence that cardiovascular disease is a major cause of death 1.
  • It is essential to note that cardiovascular disease can often be prevented, which has significant implications for morbidity, mortality, and quality of life.

Clinical Implications

  • The fact that cardiovascular disease is the single most important cause of death for both men and women has significant implications for clinical practice, emphasizing the need for effective prevention and management strategies.
  • Healthcare providers should prioritize cardiovascular disease prevention and management to reduce morbidity, mortality, and improve quality of life for their patients.
  • The evidence from the European Heart Journal study 1 supports the importance of addressing cardiovascular disease as a major public health concern.

From the Research

Causes of Death

The provided studies do not directly address the cause of death. However, they discuss palliative care, end-of-life care, and the management of symptoms and suffering in patients with serious illnesses.

Palliative Care and End-of-Life Care

  • Palliative care is an approach to care that aims to reduce suffering through the management of medical symptoms, psychosocial issues, spiritual well-being, and setting goals of care 2.
  • Palliative care can be delivered in parallel with life-sustaining or life-prolonging care, and it affirms life while regarding death as a normal process 3.
  • End-of-life care encompasses three palliative care modalities: life-prolonging palliative therapy, restorative palliative care, and symptom-oriented palliative care 4.
  • Hospice care is a type of palliative care provided at the end of life, which provides comprehensive comfort care for patients and support for family members 5.

Research and Improvements

  • There is a need for more research in palliative and end-of-life care to improve the quality of care for patients with life-limiting conditions and their family members 6.
  • The current state of research challenges and opportunities in acute care surgery highlights the need for more high-quality research to guide the selection of palliative care interventions 3.
  • Palliative care education, manpower, infrastructure, and legal and policy frameworks require further improvement 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Palliative medicine and end-of-life care.

Handbook of clinical neurology, 2019

Research

End-of-Life Care: Hospice Care.

FP essentials, 2020

Research

Palliative and End-of-Life Care: More Work is Required.

International journal of environmental research and public health, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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