What is the recommended dosage of Augmentin (amoxicillin/clavulanate) for a 7-year-old child with a 250mg/ml formulation?

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Augmentin Dosage for a 7-Year-Old Child

For a 7-year-old child, the recommended Augmentin dosage depends on the child's weight and infection severity: for mild-to-moderate infections, use 25 mg/kg/day (amoxicillin component) divided every 12 hours or 20 mg/kg/day divided every 8 hours; for severe infections or those requiring higher dosing (such as resistant organisms), use 45 mg/kg/day divided every 12 hours or 40 mg/kg/day divided every 8 hours. 1

Weight-Based Dosing Algorithm

For children weighing less than 40 kg (which includes most 7-year-olds):

Mild-to-Moderate Infections

  • 25 mg/kg/day divided every 12 hours (twice daily), OR
  • 20 mg/kg/day divided every 8 hours (three times daily) 1

Severe Infections or Resistant Pathogens

  • 45 mg/kg/day divided every 12 hours (twice daily), OR
  • 40 mg/kg/day divided every 8 hours (three times daily) 1

Practical Dosing with 250 mg/5 mL Suspension

If using the 250 mg/5 mL oral suspension formulation:

For a typical 7-year-old weighing approximately 23 kg:

  • Mild-to-moderate infections: 5.75 mL (287.5 mg) twice daily, OR 3.8 mL (190 mg) three times daily 1
  • Severe infections: 10.4 mL (520 mg) twice daily, OR 7 mL (350 mg) three times daily 1

For a 7-year-old weighing approximately 30 kg:

  • Mild-to-moderate infections: 7.5 mL (375 mg) twice daily, OR 5 mL (250 mg) three times daily 1
  • Severe infections: 13.5 mL (675 mg) twice daily, OR 9 mL (450 mg) three times daily 1

Clinical Context for Dosing Selection

Choose the higher dosing regimen (45 mg/kg/day) when:

  • Treating acute otitis media with risk factors for resistant organisms 2
  • Managing infections in areas with high rates of penicillin-resistant Streptococcus pneumoniae 3
  • Treating persistent or recurrent infections 2
  • Managing lower respiratory tract infections 1

The standard dosing regimen (25 mg/kg/day) is appropriate for:

  • Uncomplicated ear, nose, and throat infections 1
  • Skin and skin structure infections 1
  • Genitourinary tract infections 1

Administration Guidelines

  • Administer at the start of meals to minimize gastrointestinal intolerance 1
  • Shake the oral suspension well before each use 1
  • Continue treatment for minimum 48-72 hours beyond symptom resolution or evidence of bacterial eradication 1
  • For Streptococcus pyogenes infections, treat for at least 10 days to prevent acute rheumatic fever 1

Important Considerations

The twice-daily dosing regimen offers advantages:

  • Improved compliance compared to three-times-daily dosing (82.8% vs 73.3% compliance) 4
  • Similar efficacy to three-times-daily regimen 4
  • Trend toward lower incidence of drug-related adverse events, particularly diarrhea (7.2% vs 10.7%) 4

Common pitfall to avoid: Do not use the 875 mg tablet formulation in children, as it is designed for adults and adolescents weighing more than 40 kg 1. The oral suspension provides more accurate weight-based dosing for pediatric patients 5.

Storage after reconstitution: Refrigeration is preferable but not required; discard any unused suspension after 14 days 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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