What are the treatment options for milia (milk spots)?

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Last updated: March 29, 2025View editorial policy

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From the Research

Milia can be effectively treated with CO2 laser therapy, as evidenced by a recent study published in 2020 1, which demonstrated successful treatment of milia-like idiopathic calcinosis cutis of the forehead in an adult without Down's syndrome. This treatment option offers a valuable alternative to traditional methods, such as manual extraction or topical creams, and can provide appealing cosmetic results. For home treatment, gentle exfoliation with a washcloth and regular cleansing with non-comedogenic products may help, while over-the-counter retinol creams can promote cell turnover and gradually reduce milia. Professional treatment options may include chemical peels containing glycolic or salicylic acid, microdermabrasion, or prescription retinoids like tretinoin 0.025-0.1% cream applied nightly, which can be recommended for multiple lesions. Some key points to consider when treating milia include:

  • Gentle exfoliation and cleansing to prevent further irritation
  • Avoiding heavy creams and using non-comedogenic products to prevent clogged pores
  • Considering professional treatment options, such as CO2 laser therapy, for persistent or bothersome lesions
  • Being aware of rare genetic conditions, such as orofaciodigital syndrome type 1, which can lead to significant morbidity if untreated, as highlighted in a study published in 2018 2. It is essential to note that most milia are harmless and may resolve spontaneously, but professional extraction or treatment can provide immediate results for bothersome lesions, as discussed in a review published in 2008 3. Additionally, a study published in 2011 4 demonstrated the efficacy and safety of erbium:YAG laser ablation of periocular milia, highlighting the importance of considering the delicate periocular region when treating milia. A study published in 2014 5 discussed the use of microdermabrasion and chemical peels in treating various cosmetic and medical skin conditions, including milia, and emphasized the need for proper screening and aftercare instructions to minimize potential complications.

References

Research

Milia: a review and classification.

Journal of the American Academy of Dermatology, 2008

Research

Periocular milia en plaque successfully treated by erbium:YAG laser ablation.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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