What are the symptoms of uveitis?

Symptoms of Uveitis

The classical symptoms of uveitis include eye pain, blurred vision, photophobia (light sensitivity), and headache, with redness of the eye being a common presenting feature. 1

Core Clinical Manifestations

The symptom profile varies by presentation pattern:

Acute Anterior Uveitis

• Sudden onset of eye pain (moderate to severe)
• Redness of the eye with or without pain
• Photophobia (light sensitivity)
• Blurred vision
• May present with tearing and eye discomfort 1

Chronic/Insidious Uveitis

When related to systemic inflammatory conditions like Crohn's disease, uveitis is frequently:

• Bilateral (affecting both eyes)
• Insidious in onset (gradual development)
• Long-lasting in duration 1

Additional Symptoms

• Floaters (spots in vision) 2
• Headache 1
• Eye discomfort or foreign body sensation 2

Critical Warning Signs

Visual disturbance, photophobia, or moderate to severe pain should prompt urgent ophthalmologic referral to prevent progression to permanent vision loss. 1 The abundant vasculature within the uvea means inflammation can rapidly lead to significant vision problems, including permanent vision loss if untreated. 1

Important Clinical Pitfalls

Symptoms are often nonspecific, making it essential to differentiate uveitis from less serious conditions like episcleritis. 1 Key distinguishing features:

• Episcleritis: Relatively painless, hyperemic (red) sclera and conjunctiva, itching and burning, no visual changes 1
• Uveitis: Eye pain, photophobia, blurred vision, and potential for vision loss 1

Any suspicious ocular signs and symptoms should be investigated by an ophthalmologist, as early detection allows initiation of treatment to prevent permanent ocular damage. 1 Slit-lamp examination is required to confirm diagnosis and differentiate between anterior and posterior uveitis. 1