What causes erythematous (red) and pruritic (itchy) cheeks?

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Last updated: March 29, 2025 • View editorial policy

Differential Diagnosis for Red Itchy Cheeks

Single Most Likely Diagnosis

  • Atopic Dermatitis (Eczema): This is the most common cause of red itchy cheeks, especially in children. It is characterized by dry, itchy, and inflamed skin, often due to allergies or genetic predisposition.

Other Likely Diagnoses

  • Contact Dermatitis: An allergic reaction or irritation from substances like makeup, soaps, or detergents can cause red itchy cheeks.
  • Rosacea: A chronic skin condition that causes redness, itching, and acne-like symptoms, often triggered by sun exposure, stress, or certain foods.
  • Seborrheic Dermatitis: A condition that causes a red, itchy rash, often on the face, due to an overgrowth of yeast on the skin.
  • Allergic Reactions: Allergies to food, pollen, or other environmental factors can cause red itchy cheeks.

Do Not Miss Diagnoses

  • Lupus: A chronic autoimmune disease that can cause a butterfly-shaped rash on the cheeks, which can be itchy and painful. Missing this diagnosis can lead to serious complications.
  • Sarcoidosis: A condition that can cause skin lesions, including red itchy cheeks, and can affect other organs if left untreated.
  • Cutaneous T-Cell Lymphoma: A rare type of skin cancer that can cause red itchy patches on the skin, including the cheeks.

Rare Diagnoses

  • Kawasaki Disease: A rare condition that causes inflammation in the blood vessels, leading to red itchy cheeks, fever, and other symptoms.
  • Erythema Multiforme: A rare skin condition that causes target-shaped lesions on the skin, including the cheeks, often due to an allergic reaction or infection.
  • Dermatomyositis: A rare autoimmune disease that causes skin rash and muscle weakness, including red itchy cheeks.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.