What is the Mitral (MI) valve?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

A passive mitral valve is a condition where the mitral valve in the heart doesn't actively close but instead relies on pressure differences between the left atrium and ventricle to function, and management focuses on treating the underlying heart failure with standard heart failure medications and potentially mitral valve repair/replacement, as indicated by the most recent study 1. This typically occurs in patients with severe left ventricular dysfunction. No specific medication directly treats a passive mitral valve itself, but treatment with ACE inhibitors or ARBs, such as lisinopril or valsartan, has been shown to reduce regurgitant fraction and volume in patients with chronic mitral regurgitation, as demonstrated in a systematic review 2. Some key points to consider in the management of a passive mitral valve include:

  • The use of beta-blockers, such as metoprolol or carvedilol, diuretics, like furosemide, and aldosterone antagonists, such as spironolactone, to manage heart failure symptoms
  • The potential need for cardiac resynchronization therapy or mitral valve repair/replacement in severe cases, as discussed in a review of mitral valve disease 3
  • The importance of regular cardiology follow-up with echocardiograms to monitor valve function and overall heart performance, as highlighted in a study on point-of-care ultrasound in the evaluation of mitral valve regurgitation 4
  • Lifestyle modifications, including sodium restriction, fluid management, and appropriate exercise as tolerated, to help manage heart failure and reduce symptoms. It's also worth noting that mitral valve disease is common and a careful understanding of mitral valve anatomy and the disease processes that affect the valve are crucial for providing optimal patient care, as emphasized in a comprehensive review of mitral valve disease 3.

References

Research

Mitral valve diseases: Pathophysiology and interventions.

Progress in cardiovascular diseases, 2021

Research

Mitral Valve Disease: a Comprehensive Review.

Current cardiology reports, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.