Pulsatile Tinnitus in the Left Ear: Diagnostic and Treatment Approach
Immediate Clinical Assessment
A patient with pulsatile tinnitus in the left ear requires urgent imaging evaluation because this symptom indicates an underlying vascular or structural abnormality in over 70% of cases, and missing life-threatening causes like dural arteriovenous fistula or arterial dissection can result in catastrophic hemorrhage or stroke. 1, 2
Critical Initial Examination Steps
Perform a focused otoscopic examination to identify:
- Vascular retrotympanic mass (suggests paraganglioma or glomus tumor—16% of pulsatile tinnitus cases) 3
- Red, pulsating mass behind tympanic membrane (pathognomonic for glomus tympanicum) 1, 3
Assess for objective versus subjective tinnitus:
- Objective tinnitus (audible to examiner with stethoscope over neck/mastoid) strongly suggests vascular pathology requiring immediate workup 1, 3
- Subjective tinnitus (patient only) still warrants comprehensive imaging in nearly all unilateral cases 1, 4
Test for venous versus arterial etiology:
- Carotid or jugular compression that relieves symptoms suggests venous etiology (sigmoid sinus abnormalities, jugular bulb variants) or arterial dissection 3
Check for red flags requiring urgent escalation:
- Focal neurological deficits (suggests stroke risk from dural AVF or dissection) 5
- Asymmetric hearing loss (requires different imaging protocol per ACR criteria) 1, 4
- Severe headache in young overweight woman (idiopathic intracranial hypertension—second most common cause at 17.5% of cases—can cause vision loss) [3, @14@]
Audiometric Testing
Obtain comprehensive audiologic examination including:
- Pure tone audiometry to detect asymmetric sensorineural hearing loss 4
- This should be performed before imaging but should not delay urgent imaging if red flags present 4
First-Line Imaging Strategy
Initial Study Selection
Order high-resolution CT temporal bone (non-contrast) as the first-line study for evaluating:
- Paragangliomas and glomus tumors 1, 3
- Jugular bulb abnormalities (high-riding jugular bulb, dehiscence of sigmoid plate) 1, 3
- Superior semicircular canal dehiscence 1, 3
- Aberrant vascular anatomy 1
Alternatively, order CT angiography (CTA) of head and neck with contrast as first-line when suspecting:
- Dural arteriovenous fistulas (8% of cases—life-threatening if missed, can cause hemorrhagic stroke) 3
- Arterial dissection (potentially fatal, requires urgent identification) 3
- Atherosclerotic carotid artery disease (most common cause at 17.5% of cases) 3
- Sigmoid sinus diverticulum or dehiscence (associated with intracranial hypertension) 1, 3
- Arteriovenous malformations 1, 3
Important Technical Consideration
CTA source images can be reconstructed to create dedicated temporal bone CT images without additional radiation exposure, though there is no evidence supporting combined CTA/temporal bone examination over sequential studies 1
When to Use MRI/MRA
Reserve MRI with contrast and MR angiography for:
- Suspected cerebellopontine angle lesions or acoustic neuroma 1
- Vascular malformations not identified on CT/CTA 1, 3
- Patients with contraindications to iodinated contrast 1
- When CT/CTA are negative but clinical suspicion remains high 3
Specific MRI sequences for comprehensive evaluation include time-of-flight MRA, arterial spin labeling, and time-resolved imaging of contrast kinetics 6
Common Diagnostic Pitfalls to Avoid
Missing dural arteriovenous fistula is the most dangerous error:
- Requires high index of suspicion as it can present with isolated pulsatile tinnitus before catastrophic hemorrhage 3
- Demands appropriate vascular imaging (CTA or catheter angiography) 1, 3
Dismissing pulsatile tinnitus as benign:
- Unlike bilateral non-pulsatile tinnitus, unilateral pulsatile tinnitus almost always requires imaging 1, 3
- Identifiable causes exist in >70% of cases 2
Inadequate otoscopic examination:
- Leads to delayed diagnosis of vascular retrotympanic masses (paragangliomas) 1, 3
- Results in inappropriate imaging selection 3
Overlooking intracranial hypertension:
- Particularly in young, overweight women with headaches 3
- Can lead to permanent vision loss if missed 3
Treatment Approach Based on Etiology
Vascular Causes
- Dural AVF: Endovascular embolization or surgical repair 5
- Arterial dissection: Anticoagulation or endovascular intervention depending on severity 3
- Carotid stenosis: Medical management or revascularization based on degree of stenosis 3
- Petrous carotid aneurysm: Stent-assisted coiling has shown success in symptom resolution 7
Structural Causes
- Paragangliomas/glomus tumors: Surgical resection, radiation therapy, or observation depending on size and symptoms 1, 3
- Superior semicircular canal dehiscence: Surgical repair if symptoms are debilitating 1, 3
- Sigmoid sinus diverticulum: Surgical repair or stenting in severe cases 1, 3
Metabolic/Systemic Causes
- Idiopathic intracranial hypertension: Weight loss, acetazolamide, lumbar puncture, or venous sinus stenting [3, @14@]
- High cardiac output states: Treat underlying condition (anemia, hyperthyroidism) 2
When No Cause Identified
If imaging is negative but symptoms persist: