What are the guidelines for ordering an ultrasound to evaluate a soft tissue mass on the medial bicep?

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Last updated: November 11, 2025View editorial policy

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How to Order an Ultrasound for a Medial Bicep Mass

For a mass on the medial bicep, order plain radiographs first, followed by ultrasound of the upper arm/bicep region if the mass appears superficial to the deep fascia. 1

Initial Imaging Algorithm

Step 1: Plain Radiographs

  • Always obtain plain radiographs of the humerus/upper arm first, even though they may seem unnecessary for a soft tissue mass 1, 2
  • Radiographs identify calcifications (27% yield), bone involvement (22% yield), and intrinsic fat (11% yield) that can be diagnostic 2
  • This step rules out phleboliths, synovial chondromatosis, myositis ossificans, or bone involvement 1

Step 2: Determine Mass Depth on Physical Examination

The key decision point is whether the mass is superficial (above the deep fascia) or deep (below the deep fascia):

If Superficial:

  • Ultrasound is highly appropriate as the next imaging study with 94.1% sensitivity and 99.7% specificity 1, 2
  • Order as: "Ultrasound of the left/right upper arm to evaluate palpable mass on medial bicep"

If Deep or Uncertain Depth:

  • Ultrasound accuracy drops precipitously for deep masses 1
  • Consider proceeding directly to MRI without and with IV contrast after radiographs 2

Ultrasound Order Specifications

What to Include in Your Order:

  • Anatomic location: "medial bicep" or "medial upper arm"
  • Side: left or right
  • Clinical indication: "palpable soft tissue mass" with size if known
  • Any concerning features: rapid growth, pain, size >5cm 3

Example Order:

"Ultrasound of the right upper arm to evaluate 2cm palpable mass on medial bicep, present for 3 months"

When Ultrasound Findings Require Further Imaging

Proceed to MRI without and with IV contrast if: 1, 2

  • Ultrasound shows atypical features (irregular margins, increased vascularity, heterogeneous echotexture)
  • Mass is solid rather than cystic with concerning characteristics
  • Mass is larger than 5cm 3
  • Deep location confirmed on ultrasound 1
  • Clinical features remain suspicious despite benign ultrasound appearance 1

Critical Pitfalls to Avoid

  • Do not skip radiographs - they are the recommended first imaging study per ACR Appropriateness Criteria, even for obvious soft tissue masses 1
  • Do not rely on ultrasound alone for deep masses - accuracy is considerably less for lesions outside subcutaneous tissue 1
  • Do not assume all superficial masses are benign - 4% of superficial masses can be malignant, requiring further imaging if features are atypical 1
  • Avoid ordering MRI first - literature does not support MRI as the initial examination for soft tissue masses 1

Additional Ultrasound Benefits for This Location

Ultrasound at the medial bicep is particularly useful for: 1

  • Differentiating solid from cystic lesions
  • Demonstrating relationship to adjacent neurovascular structures (important given proximity to brachial artery and median/ulnar nerves)
  • Identifying lipomas with characteristic curved echogenic lines and minimal vascularity 1
  • Confirming ganglion cysts if clinically suspected 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Evaluation and Management of Superficial Hand Masses

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Imaging for Lipoma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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